Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 2/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | YARS1 | P54577 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | NPY1R | P25929 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | HK2 | P52789 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15631155 | 0.71 | ALOX5 (0.53) | ADRB2ADRB1ADRB3ADRA2AADRA2B | |
| SCHEMBL15631302 | 0.70 | ADRA1A (0.57) | ADRB2ADRB1ADRB3ADRA2AADRA2B | |
| SCHEMBL9095138 | 0.70 | ADRA2A (0.58) | ADRB2ADRB1ADRB3ADRA2AADRA2B | |
| SCHEMBL9095132 | 0.70 | ADRA2A (0.58) | ADRB2ADRB1ADRB3ADRA2AADRA2B | |
| SCHEMBL19426095 | 0.69 | ALDH1A1 (0.41) | ADRB2ADRB1ADRB3ADRA2AADRA2B | |
| SCHEMBL19426170 | 0.68 | ADRA2A (0.49) | ADRB2ADRB1ADRB3ADRA2AADRA2B | |
| SCHEMBL11479086 | 0.67 | ESR1 (0.43) | ALOX5YARS1ESR1ESR2KDM4E | |
| SCHEMBL19426105 | 0.67 | ADRA2A (0.47) | ADRB2ADRB1ADRB3ADRA2AADRA2B | |
| SCHEMBL19426188 | 0.67 | ADRB2 (0.39) | ADRB2ADRB1ADRB3ADRA2AADRA2B | |
| SCHEMBL11851290 | 0.66 | ADRB2 (1.00) | ADRB2ADRB1ADRB3ADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170281532-A1 | 2 SUBSTITUTED CEPHEM COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2017-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170281532-A1 | 2 SUBSTITUTED CEPHEM COMPOUNDS | CEP170, CES2, CMBL | ADRB2 2846/4885ADRB1 3823/4885ADRB3 3990/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.