Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | NAAA | Q02083 | 2/20 | 0.40 |
| ▸ | CTRC | Q99895 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4773215 | 1.00 | NR1I2 (0.50) | NR1I2NAAACTRCHTR2AASAH1 | |
| SCHEMBL11091808 | 1.00 | NR1I2 (0.50) | NR1I2NAAACTRCHTR2AASAH1 | |
| SCHEMBL11518709 | 1.00 | NR1I2 (0.50) | NR1I2NAAACTRCHTR2AASAH1 | |
| SCHEMBL28414078 | 1.00 | NR1I2 (0.50) | NR1I2NAAACTRCHTR2AASAH1 | |
| SCHEMBL11519233 | 1.00 | NR1I2 (0.50) | NR1I2NAAACTRCHTR2AASAH1 | |
| SCHEMBL4004094 | 0.97 | NR1I2 (0.47) | NR1I2NAAACTRCHTR2AASAH1 | |
| SCHEMBL8030244 | 0.97 | NR1I2 (0.47) | NR1I2NAAACTRCHTR2AASAH1 | |
| SCHEMBL8024763 | 0.97 | NR1I2 (0.47) | NR1I2NAAACTRCHTR2AASAH1 | |
| SCHEMBL8014431 | 0.97 | NR1I2 (0.47) | NR1I2NAAACTRCHTR2AASAH1 | |
| Potassium Ion SCHEMBL10982840 | 0.97 | NR1I2 (0.47) | NR1I2NAAACTRCHTR2AASAH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 345 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110432269-B | Stable peroxyacetic acid disinfectant and preparation method thereof | 浙江佰克医疗技术有限公司 | 2022-04-22 | — | — | CN | claimed |
| EP-2120842-B1 | HYBRID ORGANIC/INORGANIC CHEMICAL HYBRID SYSTEMS, INCLUDING FUNCTIONALIZED CALCIUM PHOSPHATE HYBRID SYSTEMS, AND A SOLID-STATE METHOD OF PRODUCING THE SAME | INDIANA NANOTECH DIVISION OF THERAMETRIC TECH INC (US) | 2019-08-21 | — | — | EP | claimed |
| EP-2658908-B1 | VULCANISABLE COMPOUNDS BASED ON NITRILE RUBBERS CONTAINING EPOXY GROUPS | ARLANXEO DEUTSCHLAND GMBH (DE) | 2018-09-19 | — | — | EP | claimed |
| EP-1986587-B1 | TOOTHPASTE FLUORIDE COMPOSITION | UNIV MELBOURNE (AU) | 2018-08-22 | — | — | EP | claimed |
| US-9868806-B2 | Compositions that can be vulcanized and that are based on nitrile rubbers containing epoxy groups | ARLANXEO DEUTSCHLAND GMBH (DE) | 2018-01-16 | — | — | US | claimed |
| US-9725547-B2 | Vulcanisable compositions based on epoxy group-containing nitrile rubbers | ARLANXEO DEUTSCHLAND GMBH (DE) | 2017-08-08 | — | — | US | claimed |
| EP-2766422-B1 | VULCANISABLE COMPOUNDS ON THE BASIS OF NITRILE RUBBERS CONTAINING EPOXY GROUPS | ARLANXEO DEUTSCHLAND GMBH (DE) | 2017-05-03 | — | — | EP | claimed |
| US-20140378618-A1 | VULCANISABLE COMPOSITIONS BASED ON EPOXY GROUP-CONTAINING NITRILE RUBBERS | ARLANXEO DEUTSCHLAND GMBH (DE) | 2014-12-25 | — | — | US | claimed |
| EP-2766422-A1 | VULCANISABLE COMPOSITIONS BASED ON EPOXY GROUP-CONTAINING NITRILE RUBBERS | LANXESS Deutschland GmbH (DE) | 2014-08-20 | — | — | EP | claimed |
| US-20140114026-A1 | COMPOSITIONS THAT CAN BE VULCANIZED AND THAT ARE BASED ON NITRILE RUBBERS CONTAINING EPOXY GROUPS | LANXESS DEUTSCHLAND GMBH (DE) | 2014-04-24 | — | — | US | claimed |
| EP-1477503-A2 | Release coatings for bitumen | Schill + Seilacher "Struktol" Aktiengesellschaft (DE) | 2004-11-17 | — | — | EP | claimed |
| EP-0985700-B1 | BIAXIALLY ORIENTED POLYESTER FILM | TEIJIN LTD (JP) | 2004-07-14 | — | — | EP | claimed |
| EP-1287819-A1 | Method of coating with antibiotics an object having interconnected microcavities and uses thereof | Heraeus Kulzer GmbH & Co.KG (DE) | 2003-03-05 | — | — | EP | claimed |
| EP-1243255-A2 | Method of preparation of antibiotic compositions | Heraeus Kulzer GmbH & Co.KG (DE) | 2002-09-25 | — | — | EP | claimed |
| EP-0604906-B1 | Water dispersible granular herbicidal compositions | AMERICAN CYANAMID CO (US) | 1999-05-26 | — | — | EP | claimed |
| US-5302486-A | Encapsulated toner process utilizing phase separation | XEROX CORPORATION (US) | 1994-04-12 | — | — | US | claimed |
| US-5283153-A | Encapsulated toner processes | XEROX CORPORATION (US) | 1994-02-01 | — | — | US | claimed |
| US-5223370-A | Low gloss toner compositions and processes thereof | XEROX CORPORATION (US) | 1993-06-29 | — | — | US | claimed |
| EP-0330889-B1 | PROCESS FOR THE PREPARATION OF NON-DUSTING, METAL-CONTAINING STABILISER GRANULATES FOR HALOGEN-CONTAINING POLYMERS | Bärlocher GmbH (DE) | 1992-09-02 | — | — | EP | claimed |
| EP-0330889-A1 | Process for the preparation of non-dusting, metal-containing stabiliser granulates for halogen-containing polymers | Bärlocher GmbH (DE) | 1989-09-06 | — | — | EP | claimed |