SCHEMBL194764

SCHEMBL194764

O=c1cc(C(F)(F)F)c2cc3c4c(c2o1)CCCN4CCC3

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 10/20 1.00
▸ KMT2A Q03164 10/20 1.00
▸ USP2 O75604 7/20 1.00
▸ TDP1 Q9NUW8 3/20 1.00
▸ HTT P42858 2/20 1.00
▸ KEAP1 Q14145 1/20 1.00
▸ NFE2L2 Q16236 1/20 1.00
▸ GPR35 Q9HC97 1/20 1.00
▸ ALDH1A1 P00352 9/20 0.63
▸ MAPT P10636 6/20 0.63
▸ HPGD P15428 6/20 0.63
▸ CASP1 P29466 6/20 0.63
▸ CASP7 P55210 6/20 0.63
▸ HSD17B10 Q99714 6/20 0.63
▸ KDM4E B2RXH2 5/20 0.63
▸ GAA P10253 5/20 0.63
▸ LMNA P02545 5/20 0.63
▸ GLA P06280 2/20 0.63
▸ ATM Q13315 2/20 0.63
▸ L3MBTL1 Q9Y468 2/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31267435 1.00 MEN1 (1.00) MEN1KMT2AUSP2TDP1HTT
SCHEMBL29787036 0.88 KMT2A (0.78) MEN1KMT2AUSP2TDP1HTT
SCHEMBL29466121 0.85 KMT2A (0.74) MEN1KMT2AUSP2TDP1HTT
SCHEMBL15398196 0.82 MEN1 (0.69) MEN1KMT2AUSP2TDP1HTT
SCHEMBL394375 0.82 MEN1 (0.73) MEN1KMT2AUSP2TDP1HTT
SCHEMBL29440640 0.82 MEN1 (0.73) MEN1KMT2AUSP2TDP1HTT
SCHEMBL1215495 0.80 KMT2A (0.67) MEN1KMT2AUSP2TDP1HTT
SCHEMBL3204368 0.79 KMT2A (0.65) MEN1KMT2AUSP2TDP1HTT
SCHEMBL903151 0.79 ALDH1A1 (0.68) MEN1KMT2AUSP2TDP1HTT
SCHEMBL15414044 0.79 KMT2A (0.65) MEN1KMT2AUSP2TDP1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1829 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12638602-B2 Metal organic framework particles as radioisotope detectors ARIZONA BOARD OF REGENTS OF BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2026-05-26 — — US claimed
US-12630857-B2 Biological indicator for determining the efficacy of a steam or heat sterilization process and its method of use TERRAGENE LLC (US) 2026-05-19 — — US claimed
US-20260083363-A1 LUMINESCENT ENZYME-BASED SENSORS TERUMO CARDIOVASCULAR SYS CORP (US) 2026-03-26 — — US claimed
EP-3998021-B1 COLORIMETRIC SENSOR FORMULATION AND USE THEREOF PROVOST FELLOWS FOUND SCHOLARS & OTHER MEMBERS BOARD COLLEGE HOLY & UND (IE) 2026-03-11 — — EP claimed
US-20250377301-A1 STABILISED FLUOROPHORES, COMPOSITIONS, METHODS OF PREPARATION, CONJUGATES THEREOF, AND METHODS OF USE FREISTAAT BAYERN LUDWIG MAXIMILIANS UNIV MUENCHEN (DE) 2025-12-11 — — US claimed
EP-4624903-A1 LIQUID SPRAY ANALYSIS Rolls-Royce plc (GB) 2025-10-01 — — EP claimed
US-20250297956-A1 LIQUID SPRAY ANALYSIS ROLLS-ROYCE PLC (GB) 2025-09-25 — — US claimed
EP-4586911-A1 LUMINESCENT ENZYME-BASED SENSORS Terumo Cardiovascular Systems Corporation (US) 2025-07-23 — — EP claimed
CN-116987401-B Organic single crystal dye laser, and preparation method and application thereof 中国科学院化学研究所 2025-03-11 — — CN claimed
US-12180378-B2 Colorimetric sensor formulation and use thereof THE PROVOST, FELLOWS, FOUNDATION SCHOLARS, AND THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH, NEAR DUBLIN (IE) 2024-12-31 — — US claimed
US-5832931-A Method for improved selectivity in photo-activation and detection of molecular diagnostic agents PHOTOGEN, INC. (US) 1998-11-10 — — US claimed
US-5829448-A ANTITUMOR PHOTOGEN, INC. (US) 1998-11-03 — — US claimed
WO-1998018398-A1 METHOD FOR IMPROVED SELECTIVITY IN PHOTO-ACTIVATION AND DETECTION OF MOLECULAR DIAGNOSTIC AGENTS PHOTOGEN, INC. (US) 1998-05-07 — — WO claimed
WO-1998018399-A1 METHOD FOR IMPROVED SELECTIVITY IN PHOTO-ACTIVATION OF MOLECULAR AGENTS PHOTOGEN, INC. (US) 1998-05-07 — — WO claimed
US-5716855-A WITH TWO ENCAPSULATED HYDROPHOBIC CHROMOGENS SELECTED SO THAT THE EMISSIONS OF ONE (WHEN EXPOSED TO LIGHT) WILL ACTIVATE THE OTHER, FOR BIOLOGICAL MARKERS SOCIETE PROLABO (FR) 1998-02-10 — — US claimed
EP-0712426-B1 FLUORESCENT LATEX COMPRISING AT LEAST TWO FLUOROCHROMES, METHOD FOR PRODUCING SAME, AND USE THEREOF PROLABO SA (FR) 1997-06-04 — — EP claimed
US-5610932-A Solid state dye laser host PHYSICAL SCIENCES, INC. (US) 1997-03-11 — — US claimed
US-5357015-A Glow discharge crosslinking of polysiloxane sol-gel glass or film BOARD OF REGENTS, THE UNIVERSITY OF TEXAS (US) 1994-10-18 — — US claimed
EP-0431452-B1 Method for the optical distinction of dental materials and material used in this method IVOCLAR AG (LI) 1994-10-05 — — EP claimed
US-4213153-A Process for the optical display of information using lasers Max-planck-Gesellschaft zur Fordenberg der Wissenschaften e.V. (DE) 1980-07-15 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12630857-B2 Biological indicator for determining the efficacy of a steam or heat sterilization process and its method of use HSF1, SPOUT1, HSPA2 MEN1 3878/4885KMT2A 4641/4885USP2 266/4885
US-20260083363-A1 LUMINESCENT ENZYME-BASED SENSORS AOX1, XDH, LPO MEN1 4487/4885KMT2A 2637/4885USP2 1507/4885
US-12638602-B2 Metal organic framework particles as radioisotope detectors SLCO1A2, SLCO4C1, SLCO2A1 MEN1 1138/4885KMT2A 2654/4885USP2 1209/4885
US-20250377301-A1 STABILISED FLUOROPHORES, COMPOSITIONS, METHODS OF PREPARATION, CONJUGATES THEREOF, AND METHODS OF USE CRY1, MKI67, IK MEN1 1974/4885KMT2A 2311/4885USP2 2994/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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