Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27475746 | 0.96 | — | — | |
| SCHEMBL27323492 | 0.92 | — | — | |
| SCHEMBL5973848 | 0.91 | — | — | |
| SCHEMBL1230385 | 0.91 | — | — | |
| SCHEMBL5973894 | 0.91 | — | — | |
| Potassium Ion SCHEMBL7978867 | 0.91 | — | — | |
| SCHEMBL5973746 | 0.91 | — | — | |
| SCHEMBL5975205 | 0.91 | — | — | |
| SCHEMBL2788788 | 0.91 | — | — | |
| SCHEMBL7718956 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8729291-B2 | Method for producing urethanes composed of di-functional aromatic amines and dialkyl carbonates | BASF SE (DE) | 2014-05-20 | — | — | US | claimed |
| CN-102675268-A | Method for preparing (1R,2R)-2-(2,3-dihydrobenzofuran-4-yl) cyclopropanemethylamine | JINAN ZHIHE MEDICAL TECHNOLOGY CO LTD | 2012-09-19 | — | — | CN | claimed |
| CN-102153501-A | Chiral nitrogen-containing heterocyclic compound, and synthesis method and application thereof | SHANGHAI INST ORGANIC CHEM | 2011-08-17 | — | — | CN | claimed |
| CN-1865259-B | Process for preparing piperidine derivative | BEIJING D VENTURE PHARM TECH | 2010-09-29 | — | — | CN | claimed |
| US-20240246934-A1 | QUINAZOLINE-BASED COMPOUND, COMPOSITION, AND APPLICATION OF QUINAZOLINE-BASED COMPOUND | BEIJING SCITECH-MQ PHARMACEUTICALS LIMITED (CN) | 2024-07-25 | — | — | US | disclosed |
| CN-115109036-B | Quinazoline compound, composition and application thereof | 北京赛特明强医药科技有限公司 | 2024-06-11 | — | — | CN | disclosed |
| EP-4293016-A1 | QUINAZOLINE-BASED COMPOUND, COMPOSITION, AND APPLICATION OF QUINAZOLINE-BASED COMPOUND | Beijing Scitech-MQ Pharmaceuticals Limited (CN) | 2023-12-20 | — | — | EP | disclosed |
| WO-2022194265-A1 | QUINAZOLINE-BASED COMPOUND, COMPOSITION, AND APPLICATION OF QUINAZOLINE-BASED COMPOUND | 北京赛特明强医药科技有限公司 | 2022-09-22 | — | — | WO | disclosed |
| CN-114560857-A | Pyrimidopyridine compound and application thereof in medicine | 广东东阳光药业有限公司 | 2022-05-31 | — | — | CN | disclosed |
| US-20180111929-A1 | COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR | PLEXXIKON INC (US) | 2018-04-26 | — | — | US | disclosed |
| CN-104557568-B | Nicotinic receptor non-competitive antagonists | 塔加西普特公司 | 2017-04-12 | — | — | CN | disclosed |
| EP-3088400-A1 | PYRROLO[2,3-B]PYRIDINE DERIVATIVES AS PROTEIN KINASE INHIBITORS | PLEXXIKON INC. (US) | 2016-11-02 | — | — | EP | disclosed |
| EP-0008795-B1 | POLYPHOSPHAZENE POLYMERS CONTAINING MONOETHEROXY AND POLYETHEROXY SUBSTITUENTS | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1983-02-09 | — | — | EP | disclosed |
| EP-0049099-A2 | Synthetic method and intermediate for piroxicam | PFIZER INC. (US) | 1982-04-07 | — | — | EP | disclosed |
| US-4289879-A | Synthetic method and intermediate for piroxicam | PFIZER INC. (US) | 1981-09-15 | — | — | US | disclosed |
| US-4258173-A | Polyphosphazene polymers containing monoetheroxy and polyetheroxy substituents | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1981-03-24 | — | — | US | disclosed |
| EP-0008795-A1 | Polyphosphazene polymers containing monoetheroxy and polyetheroxy substituents | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1980-03-19 | — | — | EP | disclosed |
| US-4152356-A | SELECTIVE CARBONYLATION OF 9,10-DIHYDROANTHRACENE TO FORM 9-FORMYL-9,10-DIHYDROANTHRACENE | EXXON RESEARCH & ENGINEERING CO. (US) | 1979-05-01 | — | — | US | disclosed |
| US-4082810-A | STEREOSELECTIVE HYDROGENATING AGENTS | ALDRICH-BORANES, INC. (US) | 1978-04-04 | — | — | US | disclosed |
| US-4059615-A | INSECTICIDE, POLYMER INTERMEDIATE | HOOKER CHEMICALS & PLASTICS CORPORATION (US) | 1977-11-22 | — | — | US | disclosed |