Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | IDH1 | O75874 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11376991 | 0.86 | LMNA (0.52) | LMNAPTGS1TRPA1CACNA1CALDH1A1 | |
| SCHEMBL2869419 | 0.85 | L3MBTL1 (0.43) | LMNAALDH1A1SMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL11951547 | 0.84 | L3MBTL1 (0.55) | LMNAPTGS1TRPA1CACNA1CALDH1A1 | |
| SCHEMBL18894564 | 0.82 | LMNA (0.48) | LMNAPTGS1TRPA1CACNA1CALDH1A1 | |
| SCHEMBL393740 | 0.82 | PTGS1 (0.52) | LMNAPTGS1TRPA1CACNA1CALDH1A1 | |
| SCHEMBL12545564 | 0.82 | TRPA1 (0.52) | LMNAPTGS1TRPA1CACNA1CALDH1A1 | |
| SCHEMBL30026088 | 0.82 | PTGS1 (0.52) | LMNAPTGS1TRPA1CACNA1CALDH1A1 | |
| SCHEMBL11951611 | 0.80 | SLC9A1 (0.50) | LMNAPTGS1TRPA1CACNA1CALDH1A1 | |
| SCHEMBL10962414 | 0.78 | RNASEH1 (0.52) | LMNAPTGS1TRPA1CACNA1CALDH1A1 | |
| SCHEMBL799129 | 0.78 | KAT6A (0.40) | LMNAALDH1A1SMN1; SMN2MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10934295-B2 | Antimicrobials and methods of making and using same | BioVersys AG (CH) | 2021-03-02 | — | — | US | disclosed |
| US-20190211018-A1 | ANTIMICROBIALS AND METHODS OF MAKING AND USING SAME | RIB-X PHARMACEUTICALS, INC. | 2019-07-11 | — | — | US | disclosed |
| WO-2017193023-A1 | ANTIMICROBIALS AND METHODS OF MAKING AND USING SAME | MELINTA THERAPEUTICS, INC. (US) | 2017-11-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10934295-B2 | Antimicrobials and methods of making and using same | LPO, MPO, OAT | LMNA 2381/4885PTGS1 767/4885TRPA1 1440/4885 |
| US-20190211018-A1 | ANTIMICROBIALS AND METHODS OF MAKING AND USING SAME | LPO, MPO, OAT | LMNA 2381/4885PTGS1 767/4885TRPA1 1440/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.