SCHEMBL19611756

SCHEMBL19611756

CC=C(C(=O)OCC1CCO1)C(Cl)(Cl)Cl

nearest known ligand 0.42

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
LMNA P02545 2/20 0.40
POLB P06746 1/20 0.40
TP53 P04637 1/20 0.33
CYP3A4 P08684 1/20 0.33
MGLL Q99685 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
PDK1 Q15118 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2271995 0.86 LMNA (0.41) ALDH1A1LMNAPOLBTP53CYP3A4
SCHEMBL4839968 0.82 LMNA (0.38) ALDH1A1LMNAPOLBTP53CYP3A4
SCHEMBL246723 0.77 ALDH1A1 (0.47) ALDH1A1LMNAPOLBTP53CYP3A4
SCHEMBL244871 0.75 ALDH1A1 (0.73) ALDH1A1LMNAPOLBTP53CYP3A4
SCHEMBL247370 0.73 MGLL (0.45) ALDH1A1LMNAPOLBTP53CYP3A4
SCHEMBL4840523 0.73 LMNA (0.32) ALDH1A1LMNAPOLB
SCHEMBL17627797 0.72 ALDH1A1 (0.50) ALDH1A1LMNAPOLBTP53CYP3A4
SCHEMBL5013481 0.70
SCHEMBL5999325 0.70 LMNA (0.55) ALDH1A1LMNAPOLBMGLLNPSR1
SCHEMBL245898 0.69 ALDH1A1 (0.46) ALDH1A1LMNAPOLBTP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3260477-B1 COMPOSITION FOR POLYMERIZATION, METHOD FOR PRODUCING SAME, COATING COMPOSITION CONTAINING SAME, METHOD FOR PRODUCING COATING COMPOSITION CONTAINING SAID COMPOSITIONS, AND METHOD FOR PRODUCING COATING FUJIFILM CORP (JP) 2022-08-24 EP disclosed
US-10428168-B2 Composition for polymerization, method for producing same, composition for a coating containing composition for polymerization, method for producing composition for a coating using composition for polymerization, and method for producing coating FUJIFILM CORPORATION (JP) 2019-10-01 US disclosed
EP-3260477-A1 COMPOSITION FOR POLYMERIZATION, METHOD FOR PRODUCING SAME, COATING COMPOSITION CONTAINING SAME, METHOD FOR PRODUCING COATING COMPOSITION CONTAINING SAID COMPOSITIONS, AND METHOD FOR PRODUCING COATING FUJIFILM Corporation (JP) 2017-12-27 EP disclosed
US-20170335041-A1 COMPOSITION FOR POLYMERIZATION, METHOD FOR PRODUCING SAME, COMPOSITION FOR A COATING CONTAINING COMPOSITION FOR POLYMERIZATION, METHOD FOR PRODUCING COMPOSITION FOR A COATING USING COMPOSITION FOR POLYMERIZATION, AND METHOD FOR PRODUCING COATING FUJIFILM CORPORATION (JP) 2017-11-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170335041-A1 COMPOSITION FOR POLYMERIZATION, METHOD FOR PRODUCING SAME, COMPOSITION FOR A COATING CONTAINING COMPOSITION FOR POLYMERIZATION, METHOD FOR PRODUCING COMPOSITION FOR A COATING USING COMPOSITION FOR POLYMERIZATION, AND METHOD FOR PRODUCING COATING BHMT2, SETDB1, MAT2B ALDH1A1 2118/4885LMNA 2799/4885POLB 323/4885
US-10428168-B2 Composition for polymerization, method for producing same, composition for a coating containing composition for polymerization, method for producing composition for a coating using composition for polymerization, and method for producing coating MMAB, SRM, AHCY ALDH1A1 1951/4885LMNA 2115/4885POLB 348/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.