Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.34 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 11/20 | 0.33 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.31 |
| ▸ | WNT3A | P56704 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 2/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19670588 | 0.90 | FGFR4 (0.38) | FAAHFGFR4CSNK1DCSNK1EPDK1 | |
| SCHEMBL19365298 | 0.87 | FGFR4 (0.43) | FAAHFGFR4CSNK1DCSNK1EWNT3A | |
| SCHEMBL17618593 | 0.86 | FAAH (0.39) | FAAHFGFR4CSNK1DCSNK1EMTOR | |
| SCHEMBL19669050 | 0.84 | TRPV1 (0.35) | FGFR4MTORPTK2WNT3ABRD4 | |
| SCHEMBL19670233 | 0.83 | FAAH (0.39) | FAAHFGFR4CSNK1DCSNK1EPDK1 | |
| SCHEMBL19670584 | 0.83 | FAAH (0.41) | FAAHFGFR4CSNK1DCSNK1EPDK1 | |
| SCHEMBL19670373 | 0.82 | KDR (0.41) | FAAHFGFR4CSNK1DCSNK1E | |
| SCHEMBL19670266 | 0.82 | FGFR4 (0.41) | FAAHFGFR4CSNK1DCSNK1EPDK1 | |
| SCHEMBL19365394 | 0.81 | FAAH (0.39) | FAAHFGFR4CSNK1DCSNK1EPDK1 | |
| SCHEMBL19365299 | 0.81 | FGFR4 (0.40) | FAAHFGFR4CSNK1DCSNK1EPDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9834558-B2 | Substituted bridged urea analogs as sirtuin modulators | GLAXOSMITHKLINE LLC (US) | 2017-12-05 | — | — | US | disclosed |