Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | PDE2A | O00408 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | WDR5 | P61964 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31090732 | 0.92 | ALDH1A1 (0.48) | CYP2A6PDE2AALDH1A1ALOX15MAPK1 | |
| SCHEMBL1970199 | 0.83 | PDE2A (0.52) | PDE2AKDM1AHAO1 | |
| SCHEMBL12353992 | 0.77 | CYP2A6 (0.44) | CYP2A6PDE2AALDH1A1ALOX15MAPK1 | |
| SCHEMBL4620762 | 0.75 | CYP2A6 (0.50) | CYP2A6PDE2AALDH1A1ALOX15WDR5 | |
| SCHEMBL17431626 | 0.73 | PDE2A (0.46) | PDE2AALDH1A1KDM1ATDP1HAO1 | |
| SCHEMBL2490889 | 0.71 | CYP2A6 (0.53) | CYP2A6ALDH1A1ALOX15MAPK1TDP1 | |
| SCHEMBL944794 | 0.71 | PDE2A (0.44) | PDE2AKDM1ACA2CA1CES2 | |
| SCHEMBL18508 | 0.71 | — | — | |
| SCHEMBL2220475 | 0.69 | TRPA1 (0.43) | PDE2AALDH1A1KDM1ATSHRCES2 | |
| SCHEMBL2900759 | 0.69 | PDE2A (0.42) | PDE2AKDM1AHAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 275 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0367771-B1 | ARYL SULPHUR PENTAFLUORIDES | MERCK PATENT GmbH (DE) | 1992-09-02 | — | — | EP | claimed |
| US-20260008760-A1 | DIPEPTIDYL PEPTIDASE 1 INHIBITORS AND USES THEREOF | INSMED INCORPORATED | 2026-01-08 | — | — | US | disclosed |
| EP-4665717-A2 | USES OF CERTAIN 1,4-OXAZEPANE-2-CARBOXAMIDES AS DPP1 INHIBITORS | Insmed Incorporated (US) | 2025-12-24 | — | — | EP | disclosed |
| US-20250353828-A1 | SUBSTITUTED BIARYL ENDOCHIN-LIKE QUINOLONES WITH ENHANCED ANTIPARASITIC ACTIVITY | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2025-11-20 | — | — | US | disclosed |
| US-20250326765-A1 | PDE4B INHIBITOR AND USE THEREOF | XIZANG HAISCO PHARMACEUTICAL CO., LTD. (CN) | 2025-10-23 | — | — | US | disclosed |
| EP-4143179-B1 | AZETIDIN-3-YLMETHANOL DERIVATIVES AS CCR6 RECEPTOR MODULATORS FOR THE TREATMENT OF CANCER | IDORSIA PHARMACEUTICALS LTD (CH) | 2025-10-22 | — | — | EP | disclosed |
| US-12435054-B2 | Therapeutic compounds and methods of use | GENENTECH, INC. (US) | 2025-10-07 | — | — | US | disclosed |
| EP-4536639-A1 | SUBSTITUTED BIARYL ENDOCHIN-LIKE QUINOLONES WITH ENHANCED ANTIPARASITIC ACTIVITY | Oregon Health & Science University (US) | 2025-04-16 | — | — | EP | disclosed |
| EP-4534540-A1 | PDE4B INHIBITOR AND USE THEREOF | Xizang Haisco Pharmaceutical Co., Ltd. (CN) | 2025-04-09 | — | — | EP | disclosed |
| CN-119768164-A | Pharmaceutical compounds for treating complement-mediated disorders | 阿雷克森制药公司 | 2025-04-04 | — | — | CN | disclosed |
| US-20050012072-A1 | Alkyl and aryl trifluoromethoxytetrafluorosulfuranes | AIR PRODUCTS AND CHEMICALS, INC. | 2005-01-20 | — | — | US | disclosed |
| EP-1498467-A1 | Alkyl and aryl trifluoromethoxytetrafluorosulfuranes | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2005-01-19 | — | — | EP | disclosed |
| US-20040249209-A1 | Process for the synthesis of aryl sulfurpentafluorides | AIR PRODUCTS AND CHEMICALS, INC. | 2004-12-09 | — | — | US | disclosed |
| EP-1484318-A1 | Process for the synthesis of aryl sulfurpentafluorides | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2004-12-08 | — | — | EP | disclosed |
| US-20040079922-A1 | Liquid crystal composition containing an optically active compound and liquid crystal electro-optical element | SEIMI CHEMICAL CO., LTD. (JP) | 2004-04-29 | — | — | US | disclosed |
| EP-1371712-A1 | LIQUID-CRYSTAL COMPOSITION CONTAINING OPTICALLY ACTIVE COMPOUND AND LIQUID-CRYSTAL ELECTROOPTIC ELEMENT | Seimi Chemical Co., Ltd. (JP) | 2003-12-17 | — | — | EP | disclosed |
| US-6140528-A | ALKYL PENTAFLUOROSULFANYL-SUBSTITUTED-BENZOATES | RHONE-POULENC AGRICULTURE LTD (GB) | 2000-10-31 | — | — | US | disclosed |
| US-6013805-A | USED AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD (GB) | 2000-01-11 | — | — | US | disclosed |
| US-5849928-A | Herbicidal isoxazole and 2-cyano-1,3-dione compounds | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1998-12-15 | — | — | US | disclosed |
| US-5055223-A | For use in liquid crystal display elements | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250353828-A1 | SUBSTITUTED BIARYL ENDOCHIN-LIKE QUINOLONES WITH ENHANCED ANTIPARASITIC ACTIVITY | EPX, TFEB, EPHX1 | CYP2A6 1044/4885PDE2A 2161/4885ALDH1A1 2498/4885 |
| US-20040249209-A1 | Process for the synthesis of aryl sulfurpentafluorides | PFAS, FLI1, AFF4 | CYP2A6 74/4885PDE2A 4432/4885ALDH1A1 589/4885 |
| US-12435054-B2 | Therapeutic compounds and methods of use | VHL, NQO1, PCSK9 | CYP2A6 1302/4885PDE2A 2180/4885ALDH1A1 547/4885 |
| US-20260008760-A1 | DIPEPTIDYL PEPTIDASE 1 INHIBITORS AND USES THEREOF | DPP9, DPP7, DPP4 | CYP2A6 130/4885PDE2A 630/4885ALDH1A1 245/4885 |
| US-20250326765-A1 | PDE4B INHIBITOR AND USE THEREOF | PDE4B, PDE4A, PDE3B | CYP2A6 565/4885PDE2A 8/4885ALDH1A1 547/4885 |
| US-20050012072-A1 | Alkyl and aryl trifluoromethoxytetrafluorosulfuranes | SF3A3, SFXN3, SF3B3 | CYP2A6 291/4885PDE2A 4559/4885ALDH1A1 3984/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.