SCHEMBL50457

SCHEMBL50457

Oc1ccc(S(F)(F)(F)(F)F)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 3/20 0.50
CA3 P07451 3/20 0.50
CA14 Q9ULX7 3/20 0.50
ALDH1A1 P00352 2/20 0.50
CYP3A4 P08684 2/20 0.50
HIF1A Q16665 2/20 0.50
HSD17B10 Q99714 2/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
CA12 O43570 2/20 0.50
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
CA4 P22748 2/20 0.50
CA9 Q16790 2/20 0.50
KDM4E B2RXH2 1/20 0.50
NPC1 O15118 1/20 0.50
GMNN O75496 1/20 0.50
LMNA P02545 1/20 0.50
MAPT P10636 1/20 0.50
TYR P14679 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17431602 0.85 NPC1 (0.54) MEN1KMT2ACA12CA1CA2
SCHEMBL17431603 0.85 NPC1 (0.54) MEN1KMT2ACA12CA1CA2
SCHEMBL1970199 0.83 PDE2A (0.52) PDE2AKDM1A
SCHEMBL17431626 0.73 PDE2A (0.46) ALDH1A1CYP3A4PDE2AESR1ESR2
SCHEMBL944794 0.71 PDE2A (0.44) CA1CA2CA9PDE2AACHE
Hydroquinone SCHEMBL460669 0.71 ALOX15 (1.00) ALOX15CA3CA14ALDH1A1CYP3A4
Hydroquinone SCHEMBL15516 0.71
Hydroquinone SCHEMBL11511669 0.71 ALOX15 (1.00) ALOX15CA3CA14ALDH1A1CYP3A4
SCHEMBL2217763 0.69 TSHR (0.43) CA14CA12CA1CA2CA4
SCHEMBL18357594 0.69 ENPP2 (0.48) CA14CA1CA2CA4KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3980770-B1 INDICATOR MATERIAL COMPRISING A POLYMERIC GEL CARRIER AND POLYMERIC INDICATOR MOOW FARM KFT (HU) 2024-01-24 EP claimed
CN-110770271-B Method for preparing functionalized fluorinated monomers, fluorinated monomers and compositions for preparing same 埃特纳科技有限公司 2023-04-18 CN claimed
US-20220404323-A1 INDICATOR MATERIAL COMPRISING A POLYMERIC GEL CARRIER AND POLYMERIC INDICATOR MOOW.FARM KFT. (HU) 2022-12-22 US claimed
US-20220213016-A1 Methods for Making Functionalized Fluorinated Monomers, Fluorinated Monomers, and Compositions for Making the Same ETNA-TEC, LTD. 2022-07-07 US claimed
CN-114174811-A Indicator material comprising a polymeric gel carrier and a polymeric indicator 穆尔农业公司 2022-03-11 CN claimed
WO-2020245616-A1 INDICATOR MATERIAL COMPRISING A POLYMERIC GEL CARRIER AND POLYMERIC INDICATOR MOOW.FARM KFT. (HU) 2020-12-10 WO claimed
EP-3635022-A1 METHODS FOR MAKING FUNCTIONALIZED FLUORINATED MONOMERS, FLUORINATED MONOMERS, AND COMPOSITIONS FOR MAKING THE SAME Etna-Tec, Ltd (US) 2020-04-15 EP claimed
CN-110770271-A Method for preparing functionalized fluorinated monomers, fluorinated monomers and compositions for preparing same 埃特纳科技有限公司 2020-02-07 CN claimed
WO-2018213850-A1 METHODS FOR MAKING FUNCTIONALIZED FLUORINATED MONOMERS, FLUORINATED MONOMERS, AND COMPOSITIONS FOR MAKING THE SAME ETNA-TEC, LTD (US) 2018-11-22 WO claimed
US-20180334416-A1 Methods for Making Functionalized Fluorinated Monomers, Fluorinated Monomers, and Compositions for Making the Same ETNA-TEC, LTD. 2018-11-22 US claimed
CN-101784522-B Proton acceptor iminium/carbocationic coupling agents LUXEMBOURG BIOTECHNOLOGIES LTD 2014-05-28 CN claimed
EP-2625164-A1 PROCESS FOR THE PREPARATION OF 3- AND 4-(PENTAFLUOROSULFANYL)BENZENES Ústav Organické Chemie A Biochemie Akademie Ved Ceské Republiky, v.v.i. (CZ) 2013-08-14 EP claimed
WO-2012045290-A1 PROCESS FOR THE PREPARATION OF 3- AND 4-(PENTAFLUOROSULFANYL)BENZENES ÚSTAV ORGANICKÉ CHEMIE A BIOCHEMIE AKADEMIE VĚD ČESKÉ REPUBLIKY, v.v.i. (CZ) 2012-04-12 WO claimed
CN-101784522-A Proton acceptor iminium/carbocationic coupling agents LUXEMBOURG BIOTECHNOLOGIES LTD 2010-07-21 CN claimed
EP-3704094-B1 MODULATORS OF THE INTEGRATED STRESS PATHWAY CALICO LIFE SCIENCES LLC (US) 2026-03-11 EP disclosed
US-20260015464-A1 COMPOUND, SURFACE TREATMENT AGENT, ARTICLE, AND METHOD FOR MANUFACTURING ARTICLE AGC Inc. (JP) 2026-01-15 US disclosed
US-12435040-B2 1,3-substituted cyclobutyl derivatives and uses thereof BAUSCH + LOMB IRELAND LIMITED (IE) 2025-10-07 US disclosed
US-6630210-B2 Liquid crystals; chemical and heat resistance; photostability MERCK GMBH (DE) 2003-10-07 US disclosed
US-20020028306-A1 Liquid crystals; chemical and heat resistance; photostability KIRSCH PEER (DE) 2002-03-07 US disclosed
US-5055223-A For use in liquid crystal display elements MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1991-10-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12435040-B2 1,3-substituted cyclobutyl derivatives and uses thereof TRPV1, TRPV3, TRPV2 ALOX15 225/4885CA3 2580/4885CA14 3006/4885
US-20220213016-A1 Methods for Making Functionalized Fluorinated Monomers, Fluorinated Monomers, and Compositions for Making the Same ALKBH3, FTO, ALK ALOX15 158/4885CA3 989/4885CA14 1786/4885
US-20020028306-A1 Liquid crystals; chemical and heat resistance; photostability ABCC1, PFDN1, CRYAB ALOX15 1311/4885CA3 1759/4885CA14 3742/4885
US-20260015464-A1 COMPOUND, SURFACE TREATMENT AGENT, ARTICLE, AND METHOD FOR MANUFACTURING ARTICLE MSR1, F12, GFRA1 ALOX15 293/4885CA3 1660/4885CA14 2280/4885
US-20180334416-A1 Methods for Making Functionalized Fluorinated Monomers, Fluorinated Monomers, and Compositions for Making the Same ALKBH3, FTO, ALK ALOX15 158/4885CA3 989/4885CA14 1786/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.