SCHEMBL197054

SCHEMBL197054

O=S(=O)(Cl)c1cc(Br)ccc1-c1ccc(Br)cc1S(=O)(=O)Cl

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S100A4 P26447 2/20 0.48
PTPRC P08575 1/20 0.42
BCL2 P10415 2/20 0.41
MCL1 Q07820 1/20 0.41
GLA P06280 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
METAP1 P53582 1/20 0.37
WDR5 P61964 2/20 0.37
CA2 P00918 2/20 0.36
CA1 P00915 1/20 0.36
CA4 P22748 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
TGM2 P21980 1/20 0.35
CES1 P23141 1/20 0.35
TSHR P16473 1/20 0.35
GAA P10253 1/20 0.34
TRPV4 Q9HBA0 2/20 0.33
LMNA P02545 1/20 0.33
HSP90AA1 P07900 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2894066 0.85 PTPRC (0.43) S100A4PTPRCSMN1; SMN2WDR5LMNA
SCHEMBL198775 0.82 LMNA (0.44) S100A4PTPRCGLASMN1; SMN2WDR5
SCHEMBL29882666 0.82 LMNA (0.44) S100A4PTPRCGLASMN1; SMN2WDR5
SCHEMBL2244585 0.80 TRPV4 (0.40) S100A4MCL1GLASMN1; SMN2WDR5
SCHEMBL1790226 0.78 FLT1 (0.39) S100A4GLASMN1; SMN2WDR5GAA
SCHEMBL1121492 0.78 WDR5 (0.53) BCL2MCL1WDR5CA9
SCHEMBL4615229 0.78 GLA (0.37) S100A4PTPRCBCL2MCL1GLA
SCHEMBL264948 0.78 EDNRB (0.45) S100A4GLASMN1; SMN2CA2CA1
SCHEMBL31470482 0.77 HSP90AA1 (0.43) S100A4PTPRCGLASMN1; SMN2CA2
SCHEMBL196908 0.77 S100A4 (0.48) S100A4PTPRCBCL2MCL1GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2519554-B1 POLYARYLENE POLYMERS AND PROCESSES FOR PREPARING DU PONT (US) 2016-03-16 EP disclosed
US-8609804-B2 Polyarylene polymers and processes for preparing E I DU PONT DE NEMOURS AND COMPANY (US) 2013-12-17 US disclosed
US-20120322973-A1 POLYARYLENE POLYMERS AND PROCESSES FOR PREPARING E I DU PONT DE NEMOURS AND COMPANY (US) 2012-12-20 US disclosed
US-20120302725-A1 POLYARYLENE IONOMERS E I DU PONT DE NEMOURS AND COMPANY (US) 2012-11-29 US disclosed
US-20120296065-A1 POLYARYLENE IONOMERS MEMBRANES EI DU PONT DE NEMOURS AND COMPANY (US) 2012-11-22 US disclosed
US-20120289678-A1 METHOD OF MAKING POLYARYLENE IONOMERS AND MEMBRANES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2012-11-15 US disclosed
EP-2519554-A2 POLYARYLENE POLYMERS AND PROCESSES FOR PREPARING E.I. Du Pont De Nemours And Company (US) 2012-11-07 EP disclosed
US-8293905-B2 Bipyridine compound, transition metal complex, and method for production of conjugated aromatic compound using the transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-23 US disclosed
US-8236920-B2 Polyarylene and process for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-08-07 US disclosed
EP-1995265-B1 POLYARYLENE AND PROCESS FOR PRODUCING THE SAME SUMITOMO CHEMICAL CO (JP) 2012-08-01 EP disclosed
WO-2011082197-A1 POLYARYLENE IONOMERIC MEMBRANES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-07-07 WO disclosed
WO-2011082167-A1 METHOD OF MAKING POLYARYLENE IONOMERS AND MEMBRANES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-07-07 WO disclosed
US-20110046336-A1 TRANSITION METAL COMPLEX AND PROCESS FOR PRODUCING CONJUGATED AROMATIC COMPOUND USING THE TRANSITION METAL COMPLEX SUMITOMO CHEMICAL COMPANY, LIMITED 2011-02-24 US disclosed
US-20100184978-A1 BIPYRIDINE COMPOUND, TRANSITION METAL COMPLEX, AND METHOD FOR PRODUCTION OF CONJUGATED AROMATIC COMPOUND USING THE TRANSITION METAL COMPLEX SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-07-22 US disclosed
EP-2192124-A1 TRANSITION METAL COMPLEX AND PROCESS FOR PRODUCING CONJUGATED AROMATIC COMPOUND WITH THE TRANSITION METAL COMPLEX Sumitomo Chemical Company, Limited (JP) 2010-06-02 EP disclosed
EP-2172470-A1 BIPYRIDINE COMPOUND, TRANSITION METAL COMPLEX, AND METHOD FOR PRODUCTION OF CONJUGATED AROMATIC COMPOUND USING THE TRANSITION METAL COMPLEX Sumitomo Chemical Company, Limited (JP) 2010-04-07 EP disclosed
US-20090326188-A1 Method for producing polyarylene SUMITOMO CHEMICAL COMPANY, LIMITED 2009-12-31 US disclosed
EP-2065420-A1 METHOD FOR PRODUCING POLYARYLENE Sumitomo Chemical Company, Limited (JP) 2009-06-03 EP disclosed
US-20090036632-A1 Polyarylene and Process for Producing the Same SUMITOMO CHEMICAL COMPANY, LIMITED 2009-02-05 US disclosed
EP-1995265-A1 POLYARYLENE AND PROCESS FOR PRODUCING THE SAME Sumitomo Chemical Company, Limited (JP) 2008-11-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110046336-A1 TRANSITION METAL COMPLEX AND PROCESS FOR PRODUCING CONJUGATED AROMATIC COMPOUND USING THE TRANSITION METAL COMPLEX C9, C5, AP1M1 S100A4 2613/4885PTPRC 4531/4885BCL2 3772/4885
US-20100184978-A1 BIPYRIDINE COMPOUND, TRANSITION METAL COMPLEX, AND METHOD FOR PRODUCTION OF CONJUGATED AROMATIC COMPOUND USING THE TRANSITION METAL COMPLEX C9, C5, AP2M1 S100A4 2758/4885PTPRC 4492/4885BCL2 2974/4885
US-20090036632-A1 Polyarylene and Process for Producing the Same CYP1A1, CYP1B1, C1R S100A4 4787/4885PTPRC 3372/4885BCL2 420/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.