Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23884962 | 0.80 | ALDH1A1 (0.45) | ALDH1A1TSHR | |
| SCHEMBL13386604 | 0.79 | ALDH1A1 (0.55) | ALDH1A1TSHRKCNA5ALOX15IDO1 | |
| SCHEMBL1934716 | 0.74 | ALDH1A1 (0.50) | ALDH1A1TSHRKCNA5 | |
| SCHEMBL9781910 | 0.71 | ALDH1A1 (0.47) | ALDH1A1TSHR | |
| SCHEMBL6947156 | 0.71 | CASP1 (0.53) | ALDH1A1TSHR | |
| SCHEMBL5225296 | 0.71 | MGLL (0.50) | ALDH1A1TSHRMEN1MAPTKMT2A | |
| SCHEMBL14028930 | 0.70 | ALDH1A1 (0.50) | ALDH1A1TSHRKCNA5MEN1KMT2A | |
| SCHEMBL14028941 | 0.70 | ALDH1A1 (0.50) | ALDH1A1TSHRKCNA5MEN1KMT2A | |
| SCHEMBL9506098 | 0.70 | L3MBTL1 (0.53) | ALDH1A1TSHRMAPT | |
| SCHEMBL14028937 | 0.70 | ALDH1A1 (0.50) | ALDH1A1TSHRKCNA5MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2748155-B1 | ISOXAZOLINE DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-12-20 | — | — | EP | disclosed |