SCHEMBL1977435

SCHEMBL1977435

O=C(OS(c1ccccc1)(c1ccccc1)c1ccccc1)C12CC3CC(CC(C3)C1)C2

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.52
CA9 Q16790 2/20 0.50
ENPP3 O14638 1/20 0.50
CA2 P00918 1/20 0.50
ENPP1 P22413 1/20 0.50
ENPP2 Q13822 1/20 0.50
ALDH1A1 P00352 6/20 0.49
GAA P10253 2/20 0.49
MAPT P10636 1/20 0.47
XBP1 P17861 1/20 0.47
P2RX7 Q99572 2/20 0.45
RECQL P46063 1/20 0.45
CA12 O43570 1/20 0.44
HPGD P15428 1/20 0.44
KMT2A Q03164 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.43
CNR2 P34972 1/20 0.43
TSHR P16473 1/20 0.42
HTT P42858 1/20 0.42
CYP17A1 P05093 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2470744 0.91 CA9 (0.45) KDM4ECA9ENPP3CA2ENPP1
SCHEMBL17292426 0.86 L3MBTL1 (0.50) KDM4ECA9ENPP3CA2ENPP1
SCHEMBL16586710 0.77 CYP17A1 (0.42) KDM4ECA9ENPP3CA2ENPP1
SCHEMBL1634162 0.76 GAA (0.72) KDM4EALDH1A1GAAMAPTXBP1
SCHEMBL16584583 0.76 CYP17A1 (0.41) KDM4ECA9ENPP3CA2ENPP1
SCHEMBL3454498 0.76 ALDH1A1 (0.51) KDM4ECA9ENPP3CA2ENPP1
SCHEMBL3454542 0.74 ALDH1A1 (0.49) KDM4ECA9ENPP3CA2ENPP1
SCHEMBL1398383 0.73 ALDH1A1 (0.48) KDM4ECA9ENPP3CA2ENPP1
SCHEMBL2775742 0.73 KDM4E (0.45) KDM4ECA9ENPP3CA2ENPP1
SCHEMBL1733254 0.71 CYP17A1 (0.73) KDM4EALDH1A1GAAMAPTXBP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230112897-A1 COMPOSITION FOR FORMING PHOTOCURABLE SILICON-CONTAINING COATING FILM NISSAN CHEMICAL CORPORATION (JP) 2023-04-13 US disclosed
US-11448961-B2 Iodonium salt, resist composition, and pattern forming process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-09-20 US disclosed
US-20210054231-A1 COMPOSITION FOR FORMING PHOTOCURABLE SILICON-CONTAINING COATING FILM NISSAN CHEMICAL CORPORATION (JP) 2021-02-25 US disclosed
US-20200081341-A1 IODONIUM SALT, RESIST COMPOSITION, AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-03-12 US disclosed
US-9989847-B2 Onium salt compound, resist composition, and pattern forming process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-06-05 US disclosed
US-9665002-B2 Onium salt compound, resist composition, and pattern forming process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-05-30 US disclosed
US-20160259242-A1 NOVEL ONIUM SALT COMPOUND, RESIST COMPOSITION, AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-09-08 US disclosed
US-20160131972-A1 NOVEL ONIUM SALT COMPOUND, RESIST COMPOSITION, AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-05-12 US disclosed
US-8431324-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2013-04-30 US disclosed
US-20110143279-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR CORPORATION (JP) 2011-06-16 US disclosed
US-20100285405-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR CORPORATION (JP) 2010-11-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160259242-A1 NOVEL ONIUM SALT COMPOUND, RESIST COMPOSITION, AND PATTERN FORMING PROCESS LIFR, NHERF1, INSR KDM4E 2501/4885CA9 379/4885ENPP3 4549/4885
US-20160131972-A1 NOVEL ONIUM SALT COMPOUND, RESIST COMPOSITION, AND PATTERN FORMING PROCESS LIFR, NHERF1, MIF KDM4E 964/4885CA9 1053/4885ENPP3 4660/4885
US-20200081341-A1 IODONIUM SALT, RESIST COMPOSITION, AND PATTERN FORMING PROCESS ETV6, ELOVL5, EEF2 KDM4E 832/4885CA9 1842/4885ENPP3 3120/4885
US-11448961-B2 Iodonium salt, resist composition, and pattern forming process ETV6, ELOVL5, EEF2 KDM4E 832/4885CA9 1842/4885ENPP3 3120/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.