Ether

Ether

SCHEMBL1978126

CCCCCCCCCCCCCCCCOS(=O)(=O)[O-].CCOCC.[Na+]

nearest known ligand 0.85

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Ether. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 known ✓ P00915 10/20 0.52
CA2 known ✓ P00918 10/20 0.52
CA12 known ✓ O43570 3/20 0.52
CA4 known ✓ P22748 2/20 0.52
FGF1 known ✓ P05230 3/20 0.39
RECQL P46063 2/20 0.85
TSHR P16473 2/20 0.85
GLA P06280 1/20 0.85
HPGD P15428 1/20 0.85
MAPK1 P28482 1/20 0.85
EPHX2 P34913 1/20 0.85
BLM P54132 1/20 0.85
CA9 Q16790 8/20 0.52
CA7 P43166 3/20 0.52
CA14 Q9ULX7 3/20 0.52
CA3 P07451 2/20 0.52
CA6 P23280 2/20 0.52
CA5A P35218 2/20 0.52
CA5B Q9Y2D0 2/20 0.52
CES2 O00748 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ether SCHEMBL11756362 1.00 RECQL (0.85) RECQLTSHRGLAHPGDMAPK1
Ether SCHEMBL7537883 1.00 RECQL (0.85) RECQLTSHRGLAHPGDMAPK1
Ether SCHEMBL15283 1.00 RECQL (0.85) RECQLTSHRGLAHPGDMAPK1
Ether SCHEMBL355997 1.00 RECQL (0.85) RECQLTSHRGLAHPGDMAPK1
Ether SCHEMBL7537830 1.00 RECQL (0.85) RECQLTSHRGLAHPGDMAPK1
Ether SCHEMBL23674209 1.00 RECQL (0.85) RECQLTSHRGLAHPGDMAPK1
Octadecyl Sulfate SCHEMBL9771950 1.00 RECQL (0.85) RECQLTSHRGLAHPGDMAPK1
Ether SCHEMBL11022896 1.00 RECQL (0.85) RECQLTSHRGLAHPGDMAPK1
Ether SCHEMBL21641350 1.00 RECQL (0.85) RECQLTSHRGLAHPGDMAPK1
Ether SCHEMBL324781 1.00 RECQL (0.85) RECQLTSHRGLAHPGDMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114349143-B Complex coacervate phase system and preparation method and application thereof 扬州大学 2023-04-14 CN claimed
CN-114349143-A Complex coacervate phase system and preparation method and application thereof 扬州大学 2022-04-15 CN claimed
CN-111134122-B Efficient spreading agent for promoting water drops to impact on super-hydrophobic surface and completely spread 中国科学院化学研究所 2021-07-27 CN claimed
CN-111658781-A Mesoscale solubilization functional active compound system and preparation method and application thereof 中国科学院化学研究所 2020-09-15 CN claimed
CN-111134122-A Efficient spreading agent for promoting water drops to impact on super-hydrophobic surface and completely spread 中国科学院化学研究所 2020-05-12 CN claimed
US-9044624-B2 Sunscreen composition SHISEIDO COMPANY, LTD. (JP) 2015-06-02 US claimed
US-20120321576-A1 SUNSCREEN COMPOSITION SHISEIDO COMPANY, LTD. (JP) 2012-12-20 US claimed
US-20120189956-A1 SOLVENT-FREE TONER PROCESSES XEROX CORPORATION (US) 2012-07-26 US claimed
WO-2024120986-A1 A TRANSPARENT LIQUID CLEANSING COMPOSITION UNILEVER IP HOLDINGS B.V. (NL) 2024-06-13 WO disclosed
EP-4356896-A1 COMPOSITION COMPRISING SURFACTANT PREPARED WITH CARBON FROM CARBON CAPTURE Unilever IP Holdings B.V. (NL) 2024-04-24 EP disclosed
WO-2024041888-A1 A SKIN CLEANSING COMPOSITION UNILEVER IP HOLDINGS B.V. (NL) 2024-02-29 WO disclosed
WO-2024028132-A1 A LIQUID CLEANSING COMPOSITION UNILEVER IP HOLDINGS B.V. (NL) 2024-02-08 WO disclosed
US-20230373200-A1 GAS AND WATER VAPOR BARRIER LAMINATE ASAHI KASEI KABUSHIKI KAISHA (JP) 2023-11-23 US disclosed
WO-2023174769-A1 A CLEANSING COMPOSITION UNILEVER IP HOLDINGS B.V. (NL) 2023-09-21 WO disclosed
EP-1384470-B1 Skin cleansing composition KAO CORP (JP) 2011-09-14 EP disclosed
US-20110142965-A1 SKIN MOISTURIZER AND WASHING FORMULATION MARY KAY INC. 2011-06-16 US disclosed
US-20060269503-A1 Skin cleansing composition KAO CORPORATION (JP) 2006-11-30 US disclosed
US-20040136942-A1 Skin cleansing composition KAO CORPORATION (JP) 2004-07-15 US disclosed
EP-1384470-A1 Skin cleansing composition KAO CORPORATION (JP) 2004-01-28 EP disclosed
US-4992107-A Mixing neutralized acid amionic surfactant slurry and molten mixture of mono- and diethanolamides to constant viscosity, heating to deaerate PARK CORPORATION (US) 1991-02-12 US disclosed