SCHEMBL197886

SCHEMBL197886

CCCCC(CC)CNC(CC)CCN

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.53
ALDH1A1 P00352 4/20 0.53
TSHR P16473 4/20 0.53
TDP1 Q9NUW8 2/20 0.50
KDM4E B2RXH2 1/20 0.36
L3MBTL1 Q9Y468 2/20 0.34
CA2 P00918 2/20 0.34
USP2 O75604 3/20 0.34
MEN1 O00255 2/20 0.34
TP53 P04637 2/20 0.34
KMT2A Q03164 2/20 0.34
CYP2D6 P10635 2/20 0.34
LMNA P02545 2/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
HIF1A Q16665 1/20 0.34
BCL2L1 Q07817 3/20 0.33
BAK1 Q16611 3/20 0.33
HTT P42858 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL197887 0.84 TSHR (0.61) CYP3A4ALDH1A1TSHRTDP1KDM4E
SCHEMBL19917720 0.83 ALDH1A1 (0.52) CYP3A4ALDH1A1TSHRTDP1MEN1
SCHEMBL197246 0.76 LMNA (0.38) CYP3A4ALDH1A1TSHRTDP1KDM4E
Propylamine SCHEMBL19834934 0.76 TSHR (0.83) CYP3A4ALDH1A1TSHRTDP1KDM4E
SCHEMBL20962107 0.75 ALDH1A1 (0.68) CYP3A4ALDH1A1TSHRTDP1L3MBTL1
SCHEMBL936358 0.75 ALDH1A1 (0.68) CYP3A4ALDH1A1TSHRTDP1L3MBTL1
SCHEMBL9759802 0.75 CYP3A4 (0.59) CYP3A4ALDH1A1TSHRTDP1KDM4E
SCHEMBL197951 0.75 ALDH1A1 (0.72) CYP3A4ALDH1A1TSHRTDP1KDM4E
SCHEMBL3877285 0.75 CYP3A4 (0.59) CYP3A4ALDH1A1TSHRTDP1KDM4E
SCHEMBL3838045 0.74 TSHR (0.64) CYP3A4ALDH1A1TSHRTDP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 154 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118480173-B Cationic polyester and preparation method and application thereof 深圳市信必递生物科技有限公司 2025-02-07 CN disclosed
CN-119285466-A Process for preparing 2, 2-dialkyl-3-acyloxypropanal SIKA技术股份公司 2025-01-10 CN disclosed
EP-3969435-B1 PROCESS FOR THE PREPARATION OF 2,2-DIALKYL-3-ACYLOXY PROPANALS SIKA TECH AG (CH) 2024-09-18 EP disclosed
CN-118480173-A Cationic polyester and preparation method and application thereof 深圳市信必递生物科技有限公司 2024-08-13 CN disclosed
EP-3642253-B1 BLOCKING AGENTS FOR AMINES, LATENT CURING AGENTS AND POLYURETHANE COMPOSITIONS SIKA TECH AG (CH) 2023-05-10 EP disclosed
US-11518736-B2 Blocking agent for amines, latent hardeners and polyurethane compositions SIKA TECHNOLOGY AG (CH) 2022-12-06 US disclosed
CN-115368824-A Fast curing migration-free compositions based on organic polymers containing silane groups SIKA技术股份公司 2022-11-22 CN disclosed
EP-3394132-B1 TWO-COMPONENT POLYURETHANE COMPOSITION SIKA TECH AG (CH) 2022-11-09 EP disclosed
EP-3394139-B1 POLYURETHANE COMPOSITION WITH LOW PLASTICIZER MIGRATION SIKA TECH AG (CH) 2022-07-20 EP disclosed
US-20220144746-A1 PROCESS FOR PRODUCING 2,2-DIALKYL-3-ACYLOXYPROPANALS SIKA TECHNOLOGY AG (CH) 2022-05-12 US disclosed
US-20080280145-A1 moisture-reactive hot-melt adhesive which comprises at least one aldimine and at least one polyurethane polymer ( polyesterurethane copolymer, polyetherurethane copolymer)which contains isocyanate groups and is solid at room temperature; bonded assembly is notable for improved adhesive SIKA TECHNOLOGY AG (CH) 2008-11-13 US disclosed
US-20080251204-A1 Reactive Polyurethane-Hot Melt Adhesive Having a Low Isocyanate-Monomer Content SIKA TECHNOLOGY AG (CH) 2008-10-16 US disclosed
WO-2008116928-A1 ALDIMINES WITH REACTIVE GROUPS COMPRISING ACTIVE HYDROGEN SIKA TECHNOLOGY AG (CH) 2008-10-02 WO disclosed
WO-2008116927-A1 METHOD FOR THE PRODUCTION OF POLYURETHANE COMPOSITIONS WITH A LOW ISOCYANATE MONOMER CONTENT SIKA TECHNOLOGY AG (CH) 2008-10-02 WO disclosed
EP-1975187-A1 Method for manufacturing polyurethane compounds with low isocyanate-monomer content Sika Technology AG (CH) 2008-10-01 EP disclosed
EP-1975190-A1 Aldimines with reactive groups containing active hydrogen Sika Technology AG (CH) 2008-10-01 EP disclosed
EP-1937740-A1 REACTIVE POLYURETHANE-HOT MELT ADHESIVE HAVING A LOW ISOCYANATE-MONOMER CONTENT Sika Technology AG (CH) 2008-07-02 EP disclosed
WO-2008052999-A1 POLYURETHANE COMPOSITION WITH GOOD INITIAL STRENGTH SIKA TECHNOLOGY AG (CH) 2008-05-08 WO disclosed
EP-1918314-A1 Polyurethane composition with high green strength Sika Technology AG (CH) 2008-05-07 EP disclosed
WO-2007036575-A1 REACTIVE POLYURETHANE-HOT MELT ADHESIVE HAVING A LOW ISOCYANATE-MONOMER CONTENT SIKA TECHNOLOGY AG (CH) 2007-04-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11518736-B2 Blocking agent for amines, latent hardeners and polyurethane compositions ODC1, KDM2B, ALKBH2 CYP3A4 3753/4885ALDH1A1 20/4885TSHR 4857/4885
US-20220144746-A1 PROCESS FOR PRODUCING 2,2-DIALKYL-3-ACYLOXYPROPANALS ADCY4, ADCY1, ADCY2 CYP3A4 2232/4885ALDH1A1 19/4885TSHR 3940/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.