Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | AKT1 | P31749 | 2/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
| ▸ | CDC25A | P30304 | 1/20 | 0.56 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.47 |
| ▸ | PRKCG | P05129 | 1/20 | 0.47 |
| ▸ | PRKCB | P05771 | 1/20 | 0.47 |
| ▸ | PRKCA | P17252 | 1/20 | 0.47 |
| ▸ | PRKCH | P24723 | 1/20 | 0.47 |
| ▸ | PRKCI | P41743 | 1/20 | 0.47 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.47 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.47 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.47 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.47 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8561854 | 0.81 | LMNA (0.61) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL19821623 | 0.81 | SMN1; SMN2 (0.66) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL31643341 | 0.80 | SMN1; SMN2 (0.49) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL19078863 | 0.80 | SMN1; SMN2 (0.40) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL29395054 | 0.79 | SMN1; SMN2 (0.64) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL28965396 | 0.79 | SMN1; SMN2 (0.73) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL19689041 | 0.79 | LMNA (0.59) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL12795706 | 0.78 | SMN1; SMN2 (0.42) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL4972574 | 0.78 | LMNA (0.86) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL20457127 | 0.78 | SMN1; SMN2 (0.49) | LMNAAKT1ESR1ADORA3CDC25A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240238427-A1 | METHODS OF TREATING AN EYE DISORDER | KODIAK SCIENCES INC. | 2024-07-18 | — | — | US | disclosed |
| US-20240209160-A1 | POLYMERIC DISPERSANTS FROM PHENYL GLYCIDYL ETHER | STEPAN COMPANY | 2024-06-27 | — | — | US | disclosed |
| US-11912784-B2 | Methods of treating an eye disorder | KODIAK SCIENCES INC. (US) | 2024-02-27 | — | — | US | disclosed |
| US-20230250133-A1 | METHODS OF PURIFYING A PRODUCT | KODIAK SCIENCES GMBH (CH) | 2023-08-10 | — | — | US | disclosed |
| US-20180147298-A1 | COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS | MODERNATX, INC. (US) | 2018-05-31 | — | — | US | disclosed |
| US-20180028664-A1 | COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS | MODERNATX, INC. (US) | 2018-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11912784-B2 | Methods of treating an eye disorder | VEGFA, FLT4, FLT1 | LMNA 3641/4885AKT1 4244/4885ESR1 4733/4885 |
| US-20230250133-A1 | METHODS OF PURIFYING A PRODUCT | RCC2, SARS1, PHAX | LMNA 1489/4885AKT1 3860/4885ESR1 4784/4885 |
| US-20240238427-A1 | METHODS OF TREATING AN EYE DISORDER | ALDH1A2, PDE6D, CRYAB | LMNA 2194/4885AKT1 4443/4885ESR1 4317/4885 |
| US-20240209160-A1 | POLYMERIC DISPERSANTS FROM PHENYL GLYCIDYL ETHER | TYR, PAOX, NAPEPLD | LMNA 4466/4885AKT1 1624/4885ESR1 2543/4885 |
| US-20180147298-A1 | COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS | HDLBP, APOB, TSG101 | LMNA 248/4885AKT1 3235/4885ESR1 4083/4885 |
| US-20180028664-A1 | COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS | HDLBP, APOB, TSG101 | LMNA 248/4885AKT1 3235/4885ESR1 4083/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.