Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14293314 | 1.00 | CA12 (0.47) | CA12CA1CA2CA9GRM3 | |
| SCHEMBL28416641 | 1.00 | CA12 (0.47) | CA12CA1CA2CA9GRM3 | |
| SCHEMBL6484170 | 0.88 | CHRNB2 (0.46) | CHRNB2CHRNA4CHRNB4CHRNA3SMN1; SMN2 | |
| SCHEMBL1942044 | 0.88 | CHRNB2 (0.46) | CHRNB2CHRNA4CHRNB4CHRNA3SMN1; SMN2 | |
| SCHEMBL3854429 | 0.88 | CHRNB2 (0.46) | CHRNB2CHRNA4CHRNB4CHRNA3SMN1; SMN2 | |
| SCHEMBL13864821 | 0.81 | ALDH1A1 (0.50) | CA12CA1CA2CA9SMN1; SMN2 | |
| SCHEMBL8489223 | 0.81 | ALDH1A1 (0.50) | CA12CA1CA2CA9SMN1; SMN2 | |
| SCHEMBL28171513 | 0.81 | CA12 (0.47) | CA12CA1CA2CA9GRM3 | |
| SCHEMBL7354982 | 0.81 | CA12 (0.47) | CA12CA1CA2CA9GRM3 | |
| SCHEMBL16426419 | 0.81 | CA12 (0.47) | CA12CA1CA2CA9GRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111171035-B | Preparation method and application of 4-phenoxyphenyl pyrazolopyrimidine amide derivative | 山东大学 | 2021-03-30 | — | — | CN | disclosed |
| CN-111171035-A | Preparation method and application of 4-phenoxyphenyl pyrazolopyrimidine amide derivative | 山东大学 | 2020-05-19 | — | — | CN | disclosed |
| US-9371275-B2 | 5-aminolevulinic acid prodrugs for use in photodynamic therapy and photodynamic diagnosis | SWEDISH PHARMA AB (SE) | 2016-06-21 | — | — | US | disclosed |
| US-9371275-B2 | 5-aminolevulinic acid prodrugs for use in photodynamic therapy and photodynamic diagnosis | SWEDISH PHARMA AB (SE) | 2016-06-21 | — | — | US | disclosed |
| US-9371275-B2 | 5-aminolevulinic acid prodrugs for use in photodynamic therapy and photodynamic diagnosis | SWEDISH PHARMA AB (SE) | 2016-06-21 | — | — | US | disclosed |
| US-20140100271-A1 | NEW 5-AMINOLEVULINIC ACID PRODRUGS FOR USE IN PHOTODYNAMIC THERAPY AND PHOTODYNAMIC DIAGNOSIS | SWEDISH PHARMA AB C/O INKUBERA AB (SE) | 2014-04-10 | — | — | US | disclosed |
| US-20110223105-A1 | NEW 5-AMINOLEVULINIC ACID PRODRUGS FOR USE IN PHOTODYNAMIC THERAPY AND PHOTODYNAMIC DIAGNOSIS | SWEDISH PHARMA AB C/O INKUBERA AB (SE) | 2011-09-15 | — | — | US | disclosed |
| US-20110223105-A1 | NEW 5-AMINOLEVULINIC ACID PRODRUGS FOR USE IN PHOTODYNAMIC THERAPY AND PHOTODYNAMIC DIAGNOSIS | SWEDISH PHARMA AB C/O INKUBERA AB (SE) | 2011-09-15 | — | — | US | disclosed |
| US-20110223105-A1 | NEW 5-AMINOLEVULINIC ACID PRODRUGS FOR USE IN PHOTODYNAMIC THERAPY AND PHOTODYNAMIC DIAGNOSIS | SWEDISH PHARMA AB C/O INKUBERA AB (SE) | 2011-09-15 | — | — | US | disclosed |
| EP-2337775-A1 | NEW 5-AMINOLEVULINIC ACID PRODRUGS FOR USE IN PHOTODYNAMIC THERAPY AND PHOTODYNAMIC DIAGNOSIS | Swedish Pharma AB (SE) | 2011-06-29 | — | — | EP | disclosed |
| WO-2010024775-A1 | NEW 5-AMINOLEVULINIC ACID PRODRUGS FOR USE IN PHOTODYNAMIC THERAPY AND PHOTODYNAMIC DIAGNOSIS | SWEDISH PHARMA AB (SE) | 2010-03-04 | — | — | WO | disclosed |
| US-6969712-B2 | Benzimidazole derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2005-11-29 | — | — | US | disclosed |
| US-20040044056-A1 | Benzimidazole derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2004-03-04 | — | — | US | disclosed |
| EP-1342717-A1 | BENZIMIDAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2003-09-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110223105-A1 | NEW 5-AMINOLEVULINIC ACID PRODRUGS FOR USE IN PHOTODYNAMIC THERAPY AND PHOTODYNAMIC DIAGNOSIS | ALAD, PKLR, ANXA5 | CA12 2586/4885CA1 3728/4885CA2 2389/4885 |
| US-20140100271-A1 | NEW 5-AMINOLEVULINIC ACID PRODRUGS FOR USE IN PHOTODYNAMIC THERAPY AND PHOTODYNAMIC DIAGNOSIS | ALAD, PPOX, ALDH7A1 | CA12 1059/4885CA1 2183/4885CA2 975/4885 |
| US-20040044056-A1 | Benzimidazole derivatives | GPR119, OPRL1, INSR | CA12 3526/4885CA1 2325/4885CA2 2550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.