Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCG1 | P19174 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 8/20 | 0.48 |
| ▸ | GRK2 | P25098 | 4/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5104880 | 0.88 | PLCG1 (0.57) | PLCG1KMT2AMEN1THRBPOLB | |
| SCHEMBL14543475 | 0.86 | PLCG1 (0.55) | PLCG1KMT2AMEN1THRBPOLB | |
| SCHEMBL14379397 | 0.84 | PLCG1 (0.59) | PLCG1KMT2AMEN1THRBPOLB | |
| SCHEMBL5375 | 0.84 | PLCG1 (0.70) | PLCG1KMT2AMEN1THRBPOLB | |
| SCHEMBL92881 | 0.80 | ALDH1A1 (0.72) | KMT2AMEN1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL19127744 | 0.80 | PLCG1 (0.64) | PLCG1KMT2AMEN1THRBPOLB | |
| SCHEMBL1941301 | 0.79 | PSIP1 (0.47) | PLCG1KMT2AMEN1POLBCYP3A4 | |
| SCHEMBL1941565 | 0.79 | GAA (0.56) | PLCG1KMT2AMEN1THRBPOLB | |
| SCHEMBL4246493 | 0.79 | SIGMAR1 (0.61) | PLCG1KMT2AMEN1THRBPOLB | |
| SCHEMBL13586189 | 0.78 | PLCG1 (0.61) | PLCG1KMT2APOLBGRK2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081757-A1 | PI3K-ALPHA INHIBITORS AND METHODS OF MAKING AND USING THE SAME | RELAY THERAPEUTICS, INC. (US) | 2023-05-11 | — | — | WO | disclosed |
| US-20230043009-A1 | A METHOD FOR PREPARING ELECTRO-CONDUCTIVE SILICONE ELASTOMER ARTICLE | ELKEM SILICONES SHANGHAI CO., LTD. (CN) | 2023-02-09 | — | — | US | disclosed |
| EP-2342220-B1 | METHODS AND SYSTEMS FOR PREDICTING MISFOLDED PROTEIN EPITOPES | UNIV BRITISH COLUMBIA (CA) | 2021-05-12 | — | — | EP | disclosed |
| WO-2021034368-A9 | CONFORMABLE THIN FILM-BASED STRAIN SENSING WITH FLEXIBLE SUBSTRATE | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2021-04-08 | — | — | WO | disclosed |
| WO-2021041671-A1 | KRAS G12D INHIBITORS | Mirati Therapeutics, Inc. (US) | 2021-03-04 | — | — | WO | disclosed |
| US-9821337-B2 | Integrated fluidjet system for stripping, prepping and coating a part | VLN ADVANCED TECHNOLOGIES INC. (CA) | 2017-11-21 | — | — | US | disclosed |
| US-20170271580-A1 | SEMICONDUCTOR MEMORY DEVICES | SAMSUNG ELECTRONICS CO., LTD (KR) | 2017-09-21 | — | — | US | disclosed |
| EP-2803518-B1 | Sealing member | HENNIGES AUTOMOTIVE SEALING SYSTEMS NORTH AMERICA INC (US) | 2017-08-23 | — | — | EP | disclosed |
| US-20170204185-A1 | B7-H3 AND B7-H4, NOVEL IMMUNOREGULATORY MOLECULES | MAYO FOUNDATION (US) | 2017-07-20 | — | — | US | disclosed |
| EP-2557625-B1 | PROCESS FOR PRODUCTION OF SEAL STRUCTURE FOR BIPOLAR BATTERY, PROCESS FOR PRODUCTION OF BIPOLAR BATTERY, SEAL STRUCTURE FOR BIPOLAR BATTERY, AND BIPOLAR BATTERY | NISSAN MOTOR (JP) | 2017-06-21 | — | — | EP | disclosed |
| US-7225630-B2 | Refrigerating cycle apparatus, air conditioning apparatus, throttle device and flow controller | MITSUBISHI DENKI KABUSHIKI KAISHA (JP) | 2007-06-05 | — | — | US | disclosed |
| EP-1786790-A1 | OXAZOLE DERIVATIVES AS HISTAMINE H3 RECEPTOR AGENTS, PREPARATION AND THERAPEUTIC USES | ELI LILLY AND COMPANY (US) | 2007-05-23 | — | — | EP | disclosed |
| US-20070082943-A1 | Process for preparation of substantially pure glimepiride | KADAM SURESH M | 2007-04-12 | — | — | US | disclosed |
| WO-2006019833-A1 | OXAZOLE DERIVATIVES AS HISTAMINE H3 RECEPTOR AGENTS, PREPARATION AND THERAPEUTIC USES | ELI LILLY AND COMPANY (US) | 2006-02-23 | — | — | WO | disclosed |
| US-6875761-B2 | Certain 1,3-disubstituted isoquinoline derivatives | EISAI CO., LTD. (JP) | 2005-04-05 | — | — | US | disclosed |
| US-20040204421-A1 | Certain 1,3-disubstituted isoquinoline derivatives | EISAI CO., LTD. | 2004-10-14 | — | — | US | disclosed |
| US-6790844-B2 | MUSCLE RELAXANTS; ANTISEROTONINE AGENT | EISAI CO., LTD (JP) | 2004-09-14 | — | — | US | disclosed |
| US-20020013460-A1 | Condensed pyridine compound | EISAI CO., LTD | 2002-01-31 | — | — | US | disclosed |
| US-6340759-B1 | ANTISPASMODIC AGENTS | EISAI CO., LTD. (JP) | 2002-01-22 | — | — | US | disclosed |
| EP-1020445-A1 | FUSED PYRIDINE DERIVATIVES | Eisai Co., Ltd. (JP) | 2000-07-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070082943-A1 | Process for preparation of substantially pure glimepiride | DPP4, GCG, GLI2 | PLCG1 4006/4885KMT2A 964/4885MEN1 3078/4885 |
| US-20020013460-A1 | Condensed pyridine compound | MUSK, HTR1A, PAX3 | PLCG1 2999/4885KMT2A 1240/4885MEN1 786/4885 |
| US-20040204421-A1 | Certain 1,3-disubstituted isoquinoline derivatives | MUSK, HTR1A, RYR1 | PLCG1 3146/4885KMT2A 1300/4885MEN1 1171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.