Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 4/20 | 0.61 |
| ▸ | MMP9 | P14780 | 2/20 | 0.61 |
| ▸ | MMP13 | P45452 | 2/20 | 0.61 |
| ▸ | MMP8 | P22894 | 1/20 | 0.61 |
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 7/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | BACE1 | P56817 | 5/20 | 0.47 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2124592 | 0.79 | MMP2 (0.59) | MMP2MMP9MMP13MMP8MAOA | |
| SCHEMBL2122001 | 0.77 | MMP2 (1.00) | MMP2MMP9MMP13MMP8MAOA | |
| SCHEMBL30540958 | 0.77 | MMP2 (1.00) | MMP2MMP9MMP13MMP8MAOA | |
| SCHEMBL2124084 | 0.77 | MMP2 (1.00) | MMP2MMP9MMP13MMP8MAOA | |
| SCHEMBL19958251 | 0.72 | MMP2 (0.88) | MMP2MMP9MMP13MMP8MAOA | |
| SCHEMBL2817800 | 0.72 | APP (0.80) | MMP2MMP9MMP13MMP8MAOA | |
| SCHEMBL3218050 | 0.72 | APP (0.80) | MMP2MMP9MMP13MMP8MAOA | |
| SCHEMBL2123091 | 0.71 | MMP2 (0.70) | MMP2MMP9MMP13MMP8MAOA | |
| SCHEMBL10084348 | 0.70 | MMP2 (0.73) | MMP2MMP9MMP13MMP8MAOA | |
| SCHEMBL16558601 | 0.70 | MMP2 (0.82) | MMP2MMP9MMP13MMP8MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180036262-A1 | CHEMICALLY MODIFIED CURCUMINS FOR USE IN THE PRODUCTION OF LIPOXINS | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2018-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180036262-A1 | CHEMICALLY MODIFIED CURCUMINS FOR USE IN THE PRODUCTION OF LIPOXINS | ALOX15B, ALOX15, ALOX12 | MMP2 691/4885MMP9 1330/4885MMP13 483/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.