Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 3/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19857006 | 0.85 | CNR1 (0.36) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL19856928 | 0.80 | CCR1 (0.35) | — | |
| SCHEMBL19856960 | 0.77 | PLA2G10 (0.38) | — | |
| SCHEMBL19856938 | 0.77 | EIF4A3 (0.32) | — | |
| SCHEMBL19856992 | 0.76 | CCR2 (0.34) | KDM4EALDH1A1MEN1KMT2AGAA | |
| SCHEMBL19856988 | 0.76 | NOD2 (0.41) | KDM4EALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL19856991 | 0.75 | SLC6A7 (0.37) | LMNASMN1; SMN2 | |
| SCHEMBL19856927 | 0.74 | KDM4E (0.34) | KDM4EALDH1A1HTTMEN1KMT2A | |
| SCHEMBL19856907 | 0.73 | HCRTR1 (0.33) | SMN1; SMN2 | |
| SCHEMBL19856981 | 0.73 | SIRT3 (0.38) | ALDH1A1LMNASMN1; SMN2TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2925857-B1 | USE OF TRPV4 ANTAGONISTS TO AMELIORATE HYDROCEPHALUS AND RELATED MATERIALS AND METHODS | UNIV INDIANA RES & TECH CORP (US) | 2018-02-14 | — | — | EP | claimed |