Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 6/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.35 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19856905 | 0.92 | BTK (0.38) | NOD2NOD1MEN1KMT2A | |
| SCHEMBL19856988 | 0.91 | NOD2 (0.41) | CNR2SMN1; SMN2NOD2NOD1NPC1 | |
| SCHEMBL19856960 | 0.91 | PLA2G10 (0.38) | CNR2NOD2NOD1 | |
| SCHEMBL19856991 | 0.90 | SLC6A7 (0.37) | CNR2SMN1; SMN2NOD2NOD1LMNA | |
| SCHEMBL19857001 | 0.87 | TRPA1 (0.40) | CNR2NOD2NOD1NPC1RAB9A | |
| SCHEMBL19856992 | 0.82 | CCR2 (0.34) | CNR2MEN1KMT2AALDH1A1 | |
| SCHEMBL19856929 | 0.81 | CCR2 (0.35) | CNR2TP53TSHRLMNA | |
| SCHEMBL19856907 | 0.81 | HCRTR1 (0.33) | CNR2SMN1; SMN2NOD2NOD1 | |
| SCHEMBL19856933 | 0.80 | HPGD (0.36) | SMN1; SMN2NOD2NOD1NPC1RAB9A | |
| SCHEMBL19857006 | 0.80 | CNR1 (0.36) | SMN1; SMN2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2925857-B1 | USE OF TRPV4 ANTAGONISTS TO AMELIORATE HYDROCEPHALUS AND RELATED MATERIALS AND METHODS | UNIV INDIANA RES & TECH CORP (US) | 2018-02-14 | — | — | EP | claimed |