Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 16/20 | 0.35 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 2/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19857006 | 0.87 | CNR1 (0.36) | — | |
| SCHEMBL19856992 | 0.83 | CCR2 (0.34) | — | |
| SCHEMBL19856941 | 0.82 | TNF (0.37) | F10 | |
| SCHEMBL19856929 | 0.82 | CCR2 (0.35) | F10 | |
| SCHEMBL19856960 | 0.81 | PLA2G10 (0.38) | KCNH2F10 | |
| SCHEMBL19856963 | 0.80 | GRM1 (0.41) | — | |
| SCHEMBL19856988 | 0.80 | NOD2 (0.41) | — | |
| SCHEMBL19856933 | 0.79 | HPGD (0.36) | — | |
| SCHEMBL19856991 | 0.78 | SLC6A7 (0.37) | — | |
| SCHEMBL19856957 | 0.77 | AVPR1A (0.34) | FFAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2925857-B1 | USE OF TRPV4 ANTAGONISTS TO AMELIORATE HYDROCEPHALUS AND RELATED MATERIALS AND METHODS | UNIV INDIANA RES & TECH CORP (US) | 2018-02-14 | — | — | EP | claimed |