Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 3/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.33 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.33 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | SPR | P35270 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19856933 | 0.91 | HPGD (0.36) | HCRTR1HCRTR2NOD2NOD1SMN1; SMN2 | |
| SCHEMBL19856988 | 0.89 | NOD2 (0.41) | NOD2NOD1SMN1; SMN2PDGFRBKDR | |
| SCHEMBL19856992 | 0.86 | CCR2 (0.34) | SPRCNR2 | |
| SCHEMBL19856960 | 0.86 | PLA2G10 (0.38) | NOD2NOD1PIK3CDCNR2 | |
| SCHEMBL19856941 | 0.84 | TNF (0.37) | NOD2NOD1 | |
| SCHEMBL19856929 | 0.84 | CCR2 (0.35) | HCRTR1HCRTR2CNR2 | |
| SCHEMBL19856991 | 0.82 | SLC6A7 (0.37) | NOD2NOD1SMN1; SMN2CNR2 | |
| SCHEMBL19856957 | 0.82 | AVPR1A (0.34) | — | |
| SCHEMBL19856975 | 0.81 | SMN1; SMN2 (0.34) | SMN1; SMN2KDR | |
| SCHEMBL19857030 | 0.81 | PLA2G10 (0.38) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2925857-B1 | USE OF TRPV4 ANTAGONISTS TO AMELIORATE HYDROCEPHALUS AND RELATED MATERIALS AND METHODS | UNIV INDIANA RES & TECH CORP (US) | 2018-02-14 | — | — | EP | claimed |