Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PLA2G10 | O15496 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19856960 | 0.94 | PLA2G10 (0.38) | NOD2NOD1CNR2PLA2G10 | |
| SCHEMBL19856991 | 0.93 | SLC6A7 (0.37) | NOD2NOD1CNR2SMN1; SMN2PLA2G10 | |
| SCHEMBL19856981 | 0.91 | SIRT3 (0.38) | NOD2NOD1CNR2NPC1RAB9A | |
| SCHEMBL19857001 | 0.90 | TRPA1 (0.40) | NOD2NOD1CNR2NPC1RAB9A | |
| SCHEMBL19856905 | 0.90 | BTK (0.38) | NOD2NOD1PLA2G10HTTMEN1 | |
| SCHEMBL19856907 | 0.89 | HCRTR1 (0.33) | NOD2NOD1CNR2SMN1; SMN2PDGFRB | |
| SCHEMBL19856933 | 0.89 | HPGD (0.36) | NOD2NOD1NPC1PKMRAB9A | |
| SCHEMBL19856992 | 0.85 | CCR2 (0.34) | CNR2KDM4EPLA2G10MEN1KMT2A | |
| SCHEMBL19856935 | 0.85 | PARP10 (0.40) | PLA2G10 | |
| SCHEMBL19856929 | 0.84 | CCR2 (0.35) | CNR2KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2925857-B1 | USE OF TRPV4 ANTAGONISTS TO AMELIORATE HYDROCEPHALUS AND RELATED MATERIALS AND METHODS | UNIV INDIANA RES & TECH CORP (US) | 2018-02-14 | — | — | EP | claimed |