Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 6/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.34 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 2/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19856991 | 0.94 | SLC6A7 (0.37) | PLA2G10CNR2NOD2NOD1 | |
| SCHEMBL19856988 | 0.94 | NOD2 (0.41) | PLA2G10CNR2NOD2NOD1 | |
| SCHEMBL19856905 | 0.92 | BTK (0.38) | PLA2G10NOD2NOD1OPRK1KCNH2 | |
| SCHEMBL19856981 | 0.91 | SIRT3 (0.38) | CNR2NOD2NOD1 | |
| SCHEMBL19856935 | 0.91 | PARP10 (0.40) | PLA2G10OPRK1KCNH2 | |
| SCHEMBL19857001 | 0.90 | TRPA1 (0.40) | CNR2NOD2NOD1 | |
| SCHEMBL19856992 | 0.87 | CCR2 (0.34) | PLA2G10CNR2CCR2HSD11B1 | |
| SCHEMBL19856952 | 0.86 | ALDH1A1 (0.39) | NOD2NOD1CCR2MCL1 | |
| SCHEMBL19856907 | 0.86 | HCRTR1 (0.33) | PIK3CDCNR2NOD2NOD1 | |
| SCHEMBL19856929 | 0.86 | CCR2 (0.35) | CNR2CCR2F10HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2925857-B1 | USE OF TRPV4 ANTAGONISTS TO AMELIORATE HYDROCEPHALUS AND RELATED MATERIALS AND METHODS | UNIV INDIANA RES & TECH CORP (US) | 2018-02-14 | — | — | EP | claimed |