Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 1/20 | 0.38 |
| ▸ | CRHR1 | P34998 | 8/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | ITGAL | P20701 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19856993 | 0.94 | PLA2G10 (0.38) | PLA2G10CRHR1HCRTR1HCRTR2CCR2 | |
| SCHEMBL19856929 | 0.91 | CCR2 (0.35) | HCRTR1HCRTR2CCR2 | |
| SCHEMBL19856992 | 0.89 | CCR2 (0.34) | PLA2G10CRHR2CCR2KMT2A | |
| SCHEMBL19857017 | 0.87 | PLA2G10 (0.37) | PLA2G10CRHR1CCR2PPARG | |
| SCHEMBL19856941 | 0.86 | TNF (0.37) | CRHR2CCR2KMT2A | |
| SCHEMBL19856933 | 0.85 | HPGD (0.36) | HCRTR1HCRTR2CCR2 | |
| SCHEMBL19856957 | 0.83 | AVPR1A (0.34) | CCR2 | |
| SCHEMBL19856975 | 0.82 | SMN1; SMN2 (0.34) | PLA2G10CCR2KMT2A | |
| SCHEMBL19856960 | 0.82 | PLA2G10 (0.38) | PLA2G10CCR2 | |
| SCHEMBL19856907 | 0.81 | HCRTR1 (0.33) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2925857-B1 | USE OF TRPV4 ANTAGONISTS TO AMELIORATE HYDROCEPHALUS AND RELATED MATERIALS AND METHODS | UNIV INDIANA RES & TECH CORP (US) | 2018-02-14 | — | — | EP | claimed |