Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
| ▸ | CFTR | P13569 | 2/20 | 0.30 |
| ▸ | CNR2 | P34972 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19856941 | 0.93 | TNF (0.37) | CCR2F10 | |
| SCHEMBL19856992 | 0.93 | CCR2 (0.34) | CCR2KDM4EHSD11B1CNR2 | |
| SCHEMBL19857030 | 0.91 | PLA2G10 (0.38) | CCR2HCRTR1HCRTR2 | |
| SCHEMBL19856969 | 0.90 | BTK (0.37) | CCR2 | |
| SCHEMBL19856910 | 0.89 | HCRTR2 (0.37) | TSHRALOX15KDM4EHCRTR1HCRTR2 | |
| SCHEMBL19856933 | 0.89 | HPGD (0.36) | CCR2HSD11B1HCRTR1HCRTR2 | |
| SCHEMBL19856957 | 0.87 | AVPR1A (0.34) | CCR2HSD11B1 | |
| SCHEMBL19856975 | 0.86 | SMN1; SMN2 (0.34) | CCR2LMNATP53F10KDM4E | |
| SCHEMBL19856993 | 0.86 | PLA2G10 (0.38) | CCR2HCRTR1HCRTR2 | |
| SCHEMBL19856960 | 0.86 | PLA2G10 (0.38) | CCR2F10HSD11B1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2925857-B1 | USE OF TRPV4 ANTAGONISTS TO AMELIORATE HYDROCEPHALUS AND RELATED MATERIALS AND METHODS | UNIV INDIANA RES & TECH CORP (US) | 2018-02-14 | — | — | EP | claimed |