SCHEMBL19859239

SCHEMBL19859239

O=C1N=C(Nc2cccc(Cl)c2)S/C1=C\c1c[nH]c2ccccc12

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKCB P05771 2/20 0.47
BCL2 P10415 1/20 0.44
MEN1 O00255 4/20 0.42
KMT2A Q03164 4/20 0.42
NPC1 O15118 3/20 0.42
RAB9A P51151 3/20 0.42
FADS1 O60427 1/20 0.42
ERBB2 P04626 1/20 0.41
PTK6 Q13882 1/20 0.41
GRM4 Q14833 1/20 0.40
KDM4E B2RXH2 4/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
SENP7 Q9BQF6 3/20 0.39
SENP8 Q96LD8 1/20 0.39
SENP6 Q9GZR1 1/20 0.39
ABL1 P00519 1/20 0.39
EGFR P00533 1/20 0.39
ABL2 P42684 1/20 0.39
ALDH1A1 P00352 2/20 0.38
LMNA P02545 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29801540 1.00 PRKCB (0.47) PRKCBBCL2MEN1KMT2ANPC1
SCHEMBL4140358 0.92 SENP7 (0.40) PRKCBMEN1KMT2ANPC1RAB9A
SCHEMBL4140360 0.92 SENP7 (0.40) PRKCBMEN1KMT2ANPC1RAB9A
SCHEMBL21074342 0.88 SENP8 (0.52) PRKCBMEN1KMT2ANPC1RAB9A
SCHEMBL29801391 0.88 SENP8 (0.52) PRKCBMEN1KMT2ANPC1RAB9A
SCHEMBL29801683 0.88 SENP7 (0.44) PRKCBMEN1KMT2ANPC1RAB9A
SCHEMBL19859149 0.88 SENP7 (0.44) PRKCBMEN1KMT2ANPC1RAB9A
SCHEMBL21048266 0.88 MIF (0.42) PRKCBMEN1KMT2ANPC1RAB9A
SCHEMBL21074378 0.88 STING1 (0.43) PRKCBMEN1KMT2AKDM4ESMN1; SMN2
SCHEMBL21048265 0.88 MIF (0.42) PRKCBMEN1KMT2ANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230000839-A1 PHARMACEUTICAL COMPOSITION FOR TREATING MULTIPLE SCLEROSIS ON BASIS OF AMPK INHIBITORY FUNCTION AND ZINC HOMEOSTASIS CONTROL FUNCTION ZINCURE CORP. (KR) 2023-01-05 US claimed
EP-4066832-A1 PHARMACEUTICAL COMPOSITION FOR TREATING MULTIPLE SCLEROSIS ON BASIS OF AMPK INHIBITORY FUNCTION AND ZINC HOMEOSTASIS CONTROL FUNCTION Zincure Corp. (KR) 2022-10-05 EP claimed
WO-2021096270-A1 PHARMACEUTICAL COMPOSITION FOR TREATING MULTIPLE SCLEROSIS ON BASIS OF AMPK INHIBITORY FUNCTION AND ZINC HOMEOSTASIS CONTROL FUNCTION 주식회사 진큐어 2021-05-20 WO claimed
US-12343335-B2 Pharmaceutical composition for treating multiple sclerosis on basis of AMPK inhibitory function and zinc homeostasis control function ZINCURE CORP. (KR) 2025-07-01 US disclosed
US-20230000839-A1 PHARMACEUTICAL COMPOSITION FOR TREATING MULTIPLE SCLEROSIS ON BASIS OF AMPK INHIBITORY FUNCTION AND ZINC HOMEOSTASIS CONTROL FUNCTION ZINCURE CORP. (KR) 2023-01-05 US disclosed
US-20230000839-A1 PHARMACEUTICAL COMPOSITION FOR TREATING MULTIPLE SCLEROSIS ON BASIS OF AMPK INHIBITORY FUNCTION AND ZINC HOMEOSTASIS CONTROL FUNCTION ZINCURE CORP. (KR) 2023-01-05 US disclosed
EP-4066832-A1 PHARMACEUTICAL COMPOSITION FOR TREATING MULTIPLE SCLEROSIS ON BASIS OF AMPK INHIBITORY FUNCTION AND ZINC HOMEOSTASIS CONTROL FUNCTION Zincure Corp. (KR) 2022-10-05 EP disclosed
EP-3498277-B1 PHARMACEUTICAL COMPOSITION FOR STROKE TREATMENT BASED ON AMPK INHIBITION ZINCURE CORP (KR) 2021-10-06 EP disclosed
WO-2021096270-A1 PHARMACEUTICAL COMPOSITION FOR TREATING MULTIPLE SCLEROSIS ON BASIS OF AMPK INHIBITORY FUNCTION AND ZINC HOMEOSTASIS CONTROL FUNCTION 주식회사 진큐어 2021-05-20 WO disclosed
EP-3498277-A1 PHARMACEUTICAL COMPOSITION FOR STROKE TREATMENT BASED ON AMPK INHIBITION Industry Academy Cooperation Foundation Of Sejong University (KR) 2019-06-19 EP disclosed
US-20190167647-A1 PHARMACEUTICAL COMPOSITION FOR STROKE TREATMENT BASED ON AMPK INHIBITION ZINCURE CORP. (KR) 2019-06-06 US disclosed
WO-2018030762-A1 PHARMACEUTICAL COMPOSITION FOR STROKE TREATMENT BASED ON AMPK INHIBITION 세종대학교산학협력단 2018-02-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230000839-A1 PHARMACEUTICAL COMPOSITION FOR TREATING MULTIPLE SCLEROSIS ON BASIS OF AMPK INHIBITORY FUNCTION AND ZINC HOMEOSTASIS CONTROL FUNCTION PRKAB1, PRKAB2, PRKAG1 PRKCB 7/4885BCL2 487/4885MEN1 3953/4885
US-20190167647-A1 PHARMACEUTICAL COMPOSITION FOR STROKE TREATMENT BASED ON AMPK INHIBITION PRKAG1, PRKAB1, PRKAG2 PRKCB 10/4885BCL2 2404/4885MEN1 3192/4885
US-12343335-B2 Pharmaceutical composition for treating multiple sclerosis on basis of AMPK inhibitory function and zinc homeostasis control function PRKAB1, PRKAB2, PRKAG1 PRKCB 7/4885BCL2 487/4885MEN1 3953/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.