SCHEMBL19876397

SCHEMBL19876397

COc1ccc(Cl)cc1-c1nc2cc(Cl)ccc2nc1Cl

nearest known ligand 0.47

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.47
KDM4E B2RXH2 2/20 0.47
AGPAT2 O15120 8/20 0.45
AMY1A P0DUB6 2/20 0.44
RECQL P46063 2/20 0.44
HPGD P15428 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
PGK1 P00558 1/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
MAPK1 P28482 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30929920 0.91 ALDH1A1 (0.54) ALDH1A1KDM4EAGPAT2RECQLHPGD
SCHEMBL19888332 0.91 ALDH1A1 (0.54) ALDH1A1KDM4EAGPAT2RECQLHPGD
SCHEMBL19876494 0.85 ALDH1A1 (0.51) ALDH1A1KDM4EAGPAT2AMY1ARECQL
SCHEMBL19876396 0.76 PIK3R1 (0.44) ALDH1A1KDM4EAGPAT2SMN1; SMN2MEN1
SCHEMBL21185983 0.75 RECQL (0.44) ALDH1A1KDM4EAGPAT2RECQLL3MBTL1
SCHEMBL6343683 0.74 ALDH1A1 (0.77) ALDH1A1KDM4EAMY1AHPGDSMN1; SMN2
SCHEMBL7699644 0.74 ALDH1A1 (0.56) ALDH1A1KDM4EAGPAT2RECQLHPGD
SCHEMBL2493822 0.74 ALDH1A1 (0.48) ALDH1A1KDM4EAGPAT2AMY1ARECQL
SCHEMBL6304236 0.74 HRH4 (0.56) ALDH1A1KDM4ESMN1; SMN2PGK1MEN1
SCHEMBL3602260 0.74 HRH4 (0.56) ALDH1A1KDM4ESMN1; SMN2PGK1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11121326-B2 Organic compound, light-emitting element, light-emitting device, electronic device and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2021-09-14 US disclosed
US-11121326-B2 Organic compound, light-emitting element, light-emitting device, electronic device and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2021-09-14 US disclosed
US-11088333-B2 2021-08-10 US disclosed
US-11088333-B2 2021-08-10 US disclosed
US-20200358003-A1 Organic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2020-11-12 US disclosed
US-20200358003-A1 Organic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2020-11-12 US disclosed
US-10734589-B2 Organic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2020-08-04 US disclosed
US-10734589-B2 Organic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2020-08-04 US disclosed
US-20180053903-A1 Organic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-02-22 US disclosed
WO-2018033820-A1 ORGANIC COMPOUND, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-02-22 WO disclosed
US-20180053903-A1 Organic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-02-22 US disclosed
WO-2018033820-A1 ORGANIC COMPOUND, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-02-22 WO disclosed
US-20180053903-A1 Organic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-02-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180053903-A1 Organic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device AOX1, RECQL, SQOR ALDH1A1 803/4885KDM4E 1426/4885AGPAT2 4502/4885
US-10734589-B2 Organic compound, light-emitting element, light-emitting device, electronic device, and lighting device AOX1, RECQL, SQOR ALDH1A1 803/4885KDM4E 1426/4885AGPAT2 4502/4885
US-20200358003-A1 Organic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device and Lighting Device AOX1, RECQL, NFE2L2 ALDH1A1 604/4885KDM4E 1310/4885AGPAT2 4407/4885
US-11088333-B2 SDHB, OGFOD1, SDHA ALDH1A1 1723/4885KDM4E 1165/4885AGPAT2 4207/4885
US-11121326-B2 Organic compound, light-emitting element, light-emitting device, electronic device and lighting device AOX1, RECQL, NFE2L2 ALDH1A1 604/4885KDM4E 1310/4885AGPAT2 4407/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.