Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 3/20 | 0.32 |
| ▸ | CHRM5 known ✓ | P08912 | 2/20 | 0.32 |
| ▸ | CHRM3 known ✓ | P20309 | 2/20 | 0.32 |
| ▸ | CHRM2 known ✓ | P08172 | 2/20 | 0.32 |
| ▸ | CHRM4 known ✓ | P08173 | 2/20 | 0.32 |
| ▸ | HTR1A known ✓ | P08908 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.32 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL11682877 | 1.00 | ALDH1A1 (0.33) | ALDH1A1LMNATSHRHSD17B10CHRM1 | |
| Water SCHEMBL15657017 | 1.00 | ALDH1A1 (0.33) | ALDH1A1LMNATSHRHSD17B10CHRM1 | |
| Water SCHEMBL6374690 | 1.00 | ALDH1A1 (0.33) | ALDH1A1LMNATSHRHSD17B10CHRM1 | |
| Water SCHEMBL10445476 | 1.00 | ALDH1A1 (0.33) | ALDH1A1LMNATSHRHSD17B10CHRM1 | |
| Water SCHEMBL8972626 | 1.00 | ALDH1A1 (0.33) | ALDH1A1LMNATSHRHSD17B10CHRM1 | |
| Water SCHEMBL38663444 | 1.00 | ALDH1A1 (0.33) | ALDH1A1LMNATSHRHSD17B10CHRM1 | |
| Water SCHEMBL4433470 | 1.00 | ALDH1A1 (0.33) | ALDH1A1LMNATSHRHSD17B10CHRM1 | |
| Water SCHEMBL12274253 | 1.00 | ALDH1A1 (0.33) | ALDH1A1LMNATSHRHSD17B10CHRM1 | |
| Water SCHEMBL5818873 | 1.00 | ALDH1A1 (0.33) | ALDH1A1LMNATSHRHSD17B10CHRM1 | |
| Water SCHEMBL31257260 | 0.97 | ALDH1A1 (0.32) | ALDH1A1LMNATSHRHSD17B10CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 322 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-121796660-B | Postoperative drainage abdomen pad and preparation method thereof | 金士达医疗（咸宁）有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-120193264-A | Method for reducing electroless copper plating and diffusion plating of laser activated flexible substrate | 电子科技大学 | 2025-06-24 | — | — | CN | claimed |
| CN-119224289-B | Six-color lymph subgroup absolute count freeze-dried pellet and preparation method and application thereof | 江西德普生物技术有限公司 | 2025-04-01 | — | — | CN | claimed |
| CN-119708951-A | Scale inhibition coating and scale inhibition coating | 佛山市法恩洁具有限公司 | 2025-03-28 | — | — | CN | claimed |
| CN-118703415-B | Fermentation medium and application thereof in preparation of teriparatide | 亿帆医药(上海)有限公司 | 2025-02-14 | — | — | CN | claimed |
| CN-119224289-A | Six-color lymph subgroup absolute count freeze-dried pellet and preparation method and application thereof | 江西德普生物技术有限公司 | 2024-12-31 | — | — | CN | claimed |
| CN-119161984-A | Breast milk microorganism normal-temperature preservation solution and preparation method and application thereof | 艾德范思(北京)医学检验实验室有限公司 | 2024-12-20 | — | — | CN | claimed |
| CN-119080720-A | Method and device for extracting and separating fucoxanthin, docosahexaenoic acid and polysaccharide from dinoflagellate FQZ-2 such as fresh water | 福建师范大学 | 2024-12-06 | — | — | CN | claimed |
| CN-114411414-B | Palladium-free electroless copper plating method for surface of flexible nanofiber membrane | 武汉纺织大学 | 2024-10-25 | — | — | CN | claimed |
| CN-118703415-A | Fermentation medium and application thereof in preparation of teriparatide | 亿帆医药(上海)有限公司 | 2024-09-27 | — | — | CN | claimed |
| CN-116656778-A | Sample preservation solution capable of digesting mucin | 郑州安图生物工程股份有限公司 | 2023-08-29 | — | — | CN | claimed |
| CN-116445333-A | Bacillus megaterium WMX and application thereof in agar desulfurization | 中国海洋大学 | 2023-07-18 | — | — | CN | claimed |
| CN-116377714-A | Composite graphene non-woven fabric, preparation method and application thereof | 江苏欣晨雅新材料有限公司 | 2023-07-04 | — | — | CN | claimed |
| CN-116370335-A | Virus protection solution for wiping and virus protection wiping product | 康码（上海）生物科技有限公司 | 2023-07-04 | — | — | CN | claimed |
| CN-116328103-A | Automatic injector and injection spring for aged pre-filled syringe | 梯瓦制药国际有限责任公司 | 2023-06-27 | — | — | CN | claimed |
| CN-116083418-A | Magnetic bead type nucleic acid extraction kit and method for extracting nucleic acid | 无锡市申瑞生物制品有限公司 | 2023-05-09 | — | — | CN | claimed |
| CN-114594243-A | high-pH antigen repairing buffer solution adapted to full-automatic immunohistochemical staining machine and preparation method thereof | 浙江莱阅病理诊断科技有限公司 | 2022-06-07 | — | — | CN | claimed |
| US-6777436-B2 | SYNERGISTIC MIXTURE OF ANGIOTENSIN INHIBITORS, BORIC ACID, ETHYLENEDIAMINETETRAACETIC ACID AND ACTIVE DRUG | SANKYO COMPANY, LIMITED (JP) | 2004-08-17 | — | — | US | claimed |
| US-20020147211-A1 | Intraocular tension lowering compositions for topical administration | SANKYO COMPANY, LIMITED (JP) | 2002-10-10 | — | — | US | claimed |
| US-5314823-A | Solution of protease, glycerol, anionic surfactant and sodium EDTA | TOMEI SANGYO KABUSHIKI KAISHA (JP) | 1994-05-24 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020147211-A1 | Intraocular tension lowering compositions for topical administration | AGT, ECE1, AGTR1 | CHRM1 1337/4885CHRM5 1184/4885CHRM3 705/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.