Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 3/20 | 0.32 |
| ▸ | CHRM5 known ✓ | P08912 | 2/20 | 0.32 |
| ▸ | CHRM3 known ✓ | P20309 | 2/20 | 0.32 |
| ▸ | CHRM2 known ✓ | P08172 | 2/20 | 0.32 |
| ▸ | CHRM4 known ✓ | P08173 | 2/20 | 0.32 |
| ▸ | HTR1A known ✓ | P08908 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.32 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL11682877 | 1.00 | ALDH1A1 (0.33) | ALDH1A1LMNATSHRHSD17B10CHRM1 | |
| Water SCHEMBL15657017 | 1.00 | ALDH1A1 (0.33) | ALDH1A1LMNATSHRHSD17B10CHRM1 | |
| Water SCHEMBL6374690 | 1.00 | ALDH1A1 (0.33) | ALDH1A1LMNATSHRHSD17B10CHRM1 | |
| Water SCHEMBL10445476 | 1.00 | ALDH1A1 (0.33) | ALDH1A1LMNATSHRHSD17B10CHRM1 | |
| Water SCHEMBL8972626 | 1.00 | ALDH1A1 (0.33) | ALDH1A1LMNATSHRHSD17B10CHRM1 | |
| Water SCHEMBL1990945 | 1.00 | ALDH1A1 (0.33) | ALDH1A1LMNATSHRHSD17B10CHRM1 | |
| Water SCHEMBL38663444 | 1.00 | ALDH1A1 (0.33) | ALDH1A1LMNATSHRHSD17B10CHRM1 | |
| Water SCHEMBL4433470 | 1.00 | ALDH1A1 (0.33) | ALDH1A1LMNATSHRHSD17B10CHRM1 | |
| Water SCHEMBL12274253 | 1.00 | ALDH1A1 (0.33) | ALDH1A1LMNATSHRHSD17B10CHRM1 | |
| Water SCHEMBL31257260 | 0.97 | ALDH1A1 (0.32) | ALDH1A1LMNATSHRHSD17B10CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118077960-B | Cigarette holder filter stick and preparation method thereof | QINGDAO RONGCHEN HEALTH TECHNOLOGY Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-119230796-A | Anionic and cationic co-doped ferric sodium pyrophosphate positive electrode material, preparation method thereof and sodium ion battery | 贵州为方能源新材料科技有限公司 | 2024-12-31 | — | — | CN | claimed |
| US-5314823-A | Solution of protease, glycerol, anionic surfactant and sodium EDTA | TOMEI SANGYO KABUSHIKI KAISHA (JP) | 1994-05-24 | — | — | US | claimed |
| JP-11319518-A | — | — | None | — | — | JP | disclosed |
| CN-118077960-B | Cigarette holder filter stick and preparation method thereof | QINGDAO RONGCHEN HEALTH TECHNOLOGY Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | disclosed |
| CN-120153053-A | Hydrotrope cleaning compositions | 陶氏环球技术有限责任公司 | 2025-06-13 | — | — | CN | disclosed |
| CN-120129707-A | Solid particles of silicone-functional copolymer, method for producing same, and cosmetic containing same | 陶氏东丽株式会社 | 2025-06-10 | — | — | CN | disclosed |
| CN-119855496-A | Aqueous antimicrobial compositions | 陶氏环球技术有限责任公司 | 2025-04-18 | — | — | CN | disclosed |
| CN-119836457-A | Two-component curable adhesive composition | 汉高股份有限及两合公司 | 2025-04-15 | — | — | CN | disclosed |
| CN-119522273-A | Cleaning composition for recycling plastics | 陶氏环球技术有限责任公司 | 2025-02-25 | — | — | CN | disclosed |
| CN-119230796-A | Anionic and cationic co-doped ferric sodium pyrophosphate positive electrode material, preparation method thereof and sodium ion battery | 贵州为方能源新材料科技有限公司 | 2024-12-31 | — | — | CN | disclosed |
| CN-1196469-C | Surfactant for use in external preparations for skin and external preparation for skin containing the same | SHOWA DENKO KK (JP) | 2005-04-13 | — | — | CN | disclosed |
| US-6777436-B2 | SYNERGISTIC MIXTURE OF ANGIOTENSIN INHIBITORS, BORIC ACID, ETHYLENEDIAMINETETRAACETIC ACID AND ACTIVE DRUG | SANKYO COMPANY, LIMITED (JP) | 2004-08-17 | — | — | US | disclosed |
| US-20020147211-A1 | Intraocular tension lowering compositions for topical administration | SANKYO COMPANY, LIMITED (JP) | 2002-10-10 | — | — | US | disclosed |
| EP-1186302-A1 | OCULAR TENSION LOWERING COMPOSITION FOR TOPICAL ADMINSTRATION | Sankyo Company, Limited (JP) | 2002-03-13 | — | — | EP | disclosed |
| CN-1303267-A | Surfactant for external preparation for skin and external preparation for skin containing the same | SHOWA DENKO KK (JP) | 2001-07-11 | — | — | CN | disclosed |
| JP-H11319518-A | METHOD FOR WASHING AND REGENERATING SEPARATION MEMBRANE OR MODULE | KUMAMOTO PREFECTURE | 1999-11-24 | — | — | JP | disclosed |
| EP-0586741-B1 | Method for cleaning a contact lens | TOMEI SANGYO KK (JP) | 1998-08-05 | — | — | EP | disclosed |
| US-5314823-A | Solution of protease, glycerol, anionic surfactant and sodium EDTA | TOMEI SANGYO KABUSHIKI KAISHA (JP) | 1994-05-24 | — | — | US | disclosed |
| EP-0586741-A1 | Method for cleaning a contact lens | Tomei Sangyo Kabushiki Kaisha (JP) | 1994-03-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020147211-A1 | Intraocular tension lowering compositions for topical administration | AGT, ECE1, AGTR1 | CHRM1 1337/4885CHRM5 1184/4885CHRM3 705/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.