Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | GABRP | O00591 | 3/20 | 0.44 |
| ▸ | GABRD | O14764 | 3/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.44 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.44 |
| ▸ | GABRE | P78334 | 3/20 | 0.44 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.44 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.44 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.44 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.44 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20763733 | 0.92 | LMNA (0.48) | LMNAGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL20528875 | 0.86 | NFKB1 (0.56) | LMNAGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL16297970 | 0.86 | LMNA (0.52) | LMNAGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL20640381 | 0.86 | LMNA (0.52) | LMNAGABRPGABRDGABRA1GABRB1 | |
| Hydrochloric Acid SCHEMBL25230713 | 0.85 | BLM (0.52) | LMNAGABRPGABRDGABRA1GABRB1 | |
| Bromide SCHEMBL20742989 | 0.85 | LMNA (0.50) | LMNAGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL17530466 | 0.83 | CYP2D6 (0.52) | LMNAGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL31040413 | 0.81 | LMNA (0.54) | LMNAGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL13521693 | 0.81 | USP2 (0.50) | HDAC3TSHRHDAC4HDAC1HDAC7 | |
| SCHEMBL20762919 | 0.80 | BLM (0.38) | LMNAGABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025021118-A9 | LIGAND-DRUG CONJUGATE AND LINKER FOR CONJUGATION | 海南先声再明医药股份有限公司 | 2025-04-03 | — | — | WO | disclosed |
| WO-2025021118-A1 | LIGAND-DRUG CONJUGATE AND LINKER FOR CONJUGATION | 海南先声再明医药股份有限公司 | 2025-01-30 | — | — | WO | disclosed |
| US-11666623-B2 | Tetramaleimide linkers and use thereof | NEWBIO THERAPEUTICS, INC. (CN) | 2023-06-06 | — | — | US | disclosed |
| US-11666623-B2 | Tetramaleimide linkers and use thereof | NEWBIO THERAPEUTICS, INC. (CN) | 2023-06-06 | — | — | US | disclosed |
| US-11471537-B2 | Oligomer extended insulin-Fc conjugates | NOVO NORDISK A/S (DK) | 2022-10-18 | — | — | US | disclosed |
| EP-3981433-A1 | COVALENT LINKERS IN ANTIBODY-DRUG CONJUGATES AND METHODS OF MAKING AND USING THE SAME | RemeGen Biosciences, Inc. (US) | 2022-04-13 | — | — | EP | disclosed |
| EP-3334462-B1 | COVALENT LINKERS IN ANTIBODY-DRUG CONJUGATES AND METHODS OF MAKING AND USING THE SAME | RC BIOTECHNOLOGIES INC (US) | 2022-01-19 | — | — | EP | disclosed |
| US-20210128668-A1 | TETRAMALEIMIDE LINKERS AND USE THEREOF | NEWBIO THERAPEUTICS, INC. (CN) | 2021-05-06 | — | — | US | disclosed |
| US-10960082-B2 | Tridentate connexon and use thereof | NEWBIO THERAPEUTICS, INC. (CN) | 2021-03-30 | — | — | US | disclosed |
| US-10772965-B2 | Covalent linkers in antibody-drug conjugates and methods of making and using the same | RC BIOTECHNOLOGIES, INC. (US) | 2020-09-15 | — | — | US | disclosed |
| EP-2949343-A1 | TRIDENTATE CONNEXON AND USE THEREOF | Newbio Therapeutics Inc. (CN) | 2015-12-02 | — | — | EP | disclosed |
| US-20130136691-A1 | GASTRIN RELEASING PEPTIDE COMPOUNDS | BRACCO IMAGING S.P.A. (IT) | 2013-05-30 | — | — | US | disclosed |
| US-8444954-B2 | Gastrin releasing peptide compounds | BRACCO IMAGING S.P.A. (IT) | 2013-05-21 | — | — | US | disclosed |
| US-8420050-B2 | Gastrin releasing peptide compounds | BRACCO IMAGING S.P.A. (IT) | 2013-04-16 | — | — | US | disclosed |
| EP-2500040-A1 | Improved Gastrin Releasing Peptide Receptor-Binding Compounds | Bracco Imaging S.p.A (IT) | 2012-09-19 | — | — | EP | disclosed |
| US-20120009122-A1 | GASTRIN RELEASING PEPTIDE COMPOUNDS | BRACCO IMAGING S.P.A. (IT) | 2012-01-12 | — | — | US | disclosed |
| US-20110250133-A1 | GASTRIN RELEASING PEPTIDE COMPOUNDS | BRACCO IMAGING S.P.A. (IT) | 2011-10-13 | — | — | US | disclosed |
| US-20110052491-A1 | GASTRIN RELEASING PEPTIDE COMPOUNDS | BRACCO IMAGING S.P.A. (IT) | 2011-03-03 | — | — | US | disclosed |
| US-20090175786-A1 | Gastrin Releasing Peptide Compounds | BRACCO IMAGING S.P.A. (IT) | 2009-07-09 | — | — | US | disclosed |
| US-20080008649-A1 | Gastrin Releasing Peptide Compounds | BRACCO IMAGING S.P.A. (IT) | 2008-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130136691-A1 | GASTRIN RELEASING PEPTIDE COMPOUNDS | GRPR, GIPR, GHRHR | LMNA 2740/4885GABRP 104/4885GABRD 195/4885 |
| US-20090175786-A1 | Gastrin Releasing Peptide Compounds | GRPR, SSTR5, GIPR | LMNA 3594/4885GABRP 419/4885GABRD 1129/4885 |
| US-20080008649-A1 | Gastrin Releasing Peptide Compounds | GRPR, SSTR5, GIPR | LMNA 3594/4885GABRP 419/4885GABRD 1129/4885 |
| US-20120009122-A1 | GASTRIN RELEASING PEPTIDE COMPOUNDS | GRPR, GIPR, CCKBR | LMNA 4181/4885GABRP 274/4885GABRD 1090/4885 |
| US-20110250133-A1 | GASTRIN RELEASING PEPTIDE COMPOUNDS | GRPR, GIPR, GHRHR | LMNA 2740/4885GABRP 104/4885GABRD 195/4885 |
| US-11471537-B2 | Oligomer extended insulin-Fc conjugates | IAPP, IDE, INSR | LMNA 4291/4885GABRP 1076/4885GABRD 2544/4885 |
| US-20110052491-A1 | GASTRIN RELEASING PEPTIDE COMPOUNDS | GRPR, GIPR, CCKBR | LMNA 2886/4885GABRP 293/4885GABRD 1757/4885 |
| US-10960082-B2 | Tridentate connexon and use thereof | DNTT, CD2, CLTA | LMNA 882/4885GABRP 1632/4885GABRD 506/4885 |
| US-20210128668-A1 | TETRAMALEIMIDE LINKERS AND USE THEREOF | MCTS1, CA14, TTL | LMNA 2753/4885GABRP 1550/4885GABRD 1760/4885 |
| US-10772965-B2 | Covalent linkers in antibody-drug conjugates and methods of making and using the same | DHFR, FCGR1A, ADCY4 | LMNA 4768/4885GABRP 1304/4885GABRD 674/4885 |
| US-11666623-B2 | Tetramaleimide linkers and use thereof | MCTS1, CA14, TTL | LMNA 2753/4885GABRP 1550/4885GABRD 1760/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.