Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICMT | O60725 | 10/20 | 0.57 |
| ▸ | CNR1 | P21554 | 3/20 | 0.54 |
| ▸ | PLK1 | P53350 | 1/20 | 0.49 |
| ▸ | HTR6 | P50406 | 2/20 | 0.48 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | CDC25A | P30304 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1989207 | 0.84 | L3MBTL1 (0.50) | ICMTCNR1PLK1HTR6CDC25A | |
| SCHEMBL1994850 | 0.82 | ICMT (0.46) | ICMTCNR1PLK1HTR6CNR2 | |
| SCHEMBL1993887 | 0.79 | ICMT (0.49) | ICMTCNR1 | |
| SCHEMBL28365671 | 0.78 | CDC25A (0.56) | ICMTCNR1PLK1HTR6CNR2 | |
| SCHEMBL2595601 | 0.76 | ICMT (0.71) | ICMTPLK1PADI4CDC25A | |
| SCHEMBL10965765 | 0.76 | ICMT (0.71) | ICMTHTR6CNR2CDC25A | |
| SCHEMBL7842723 | 0.76 | HTR6 (0.49) | ICMTCNR1HTR6 | |
| SCHEMBL1993250 | 0.75 | ROCK2 (0.50) | CNR1PADI4CNR2 | |
| SCHEMBL5253839 | 0.75 | ICMT (0.69) | ICMTCNR2CDC25A | |
| SCHEMBL13949764 | 0.75 | CNR1 (0.48) | ICMTCNR1HTR6PADI4CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | ABBOTT LABORATORIES (US) | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | TPMT, TSLP, THPO | ICMT 1684/4885CNR1 215/4885PLK1 2596/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.