Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICMT | O60725 | 15/20 | 0.49 |
| ▸ | CNR1 | P21554 | 3/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1991929 | 0.79 | ICMT (0.57) | ICMTCNR1 | |
| SCHEMBL1994265 | 0.68 | PTGDR2 (0.42) | ICMTPTGDR2FABP4 | |
| SCHEMBL1989207 | 0.65 | L3MBTL1 (0.50) | ICMTCNR1 | |
| SCHEMBL1990987 | 0.64 | L3MBTL1 (0.45) | ICMTPTGDR2FABP4 | |
| SCHEMBL1994850 | 0.64 | ICMT (0.46) | ICMTCNR1 | |
| SCHEMBL18260434 | 0.63 | MAPT (0.40) | — | |
| SCHEMBL1993250 | 0.62 | ROCK2 (0.50) | CNR1 | |
| SCHEMBL399968 | 0.60 | ALDH1A1 (0.52) | ICMTPTGDR2 | |
| SCHEMBL11182311 | 0.60 | ALOX5 (0.39) | ICMTFABP4 | |
| SCHEMBL30901636 | 0.60 | GAA (0.37) | FABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | ABBOTT LABORATORIES (US) | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | TPMT, TSLP, THPO | ICMT 1684/4885CNR1 215/4885PTGDR2 61/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.