SCHEMBL19923490

SCHEMBL19923490

CC1C(=O)N([Si](C)(C)C)C(=O)N1C1CCCCC1

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.36
POLB P06746 1/20 0.36
GAA P10253 1/20 0.36
OPRM1 P35372 1/20 0.35
OPRL1 P41146 1/20 0.35
BRD4 O60885 3/20 0.33
NPSR1 Q6W5P4 2/20 0.33
TSHR P16473 2/20 0.33
ALDH1A1 P00352 3/20 0.33
KMT2A Q03164 2/20 0.33
TP53 P04637 1/20 0.33
MEN1 O00255 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19923461 0.82 OPRM1 (0.38) LMNAPOLBGAAOPRM1OPRL1
SCHEMBL19923668 0.81 OPRM1 (0.38) LMNAPOLBGAAOPRM1OPRL1
SCHEMBL19923528 0.79 OPRM1 (0.38) LMNAOPRM1OPRL1BRD4ALDH1A1
SCHEMBL19923763 0.77 BRD4 (0.38) LMNAGAAOPRM1OPRL1BRD4
SCHEMBL19923539 0.77 LMNA (0.46) LMNAPOLBGAAOPRM1OPRL1
SCHEMBL19923457 0.74 ALDH1A1 (0.49) LMNANPSR1TSHRALDH1A1KMT2A
SCHEMBL19923658 0.67 ADRA2C (0.35) KMT2AMEN1
SCHEMBL19923439 0.67
SCHEMBL19923627 0.67 CTSG (0.41) LMNAPOLBGAANPSR1TSHR
SCHEMBL11036434 0.65 ALDH1A1 (0.37) LMNAALDH1A1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 US claimed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 US claimed
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 US disclosed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS PARG, HNMT, PARN LMNA 336/4885POLB 803/4885GAA 2725/4885
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds HNMT, PARG, PAM LMNA 455/4885POLB 985/4885GAA 2802/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.