SCHEMBL19923724

SCHEMBL19923724

CC(C)[Si](C(C)C)(C(C)C)N1C(=O)C(c2ccccc2)N([Si](C(C)C)(C(C)C)C(C)C)C1=O

nearest known ligand 0.35

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 6/20 0.35
ALDH1A1 P00352 3/20 0.33
GFER P55789 1/20 0.33
KMT2A Q03164 3/20 0.33
TSHR P16473 1/20 0.33
HPGD P15428 2/20 0.32
MEN1 O00255 2/20 0.32
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32
RAB9A P51151 1/20 0.32
ATM Q13315 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
LMNA P02545 2/20 0.31
ADORA3 P0DMS8 1/20 0.31
KDM4E B2RXH2 1/20 0.31
GLA P06280 1/20 0.31
HSD17B10 Q99714 1/20 0.31
RIPK1 Q13546 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19923552 0.83 GAA (0.40) ALDH1A1GFERKMT2ATSHRMEN1
SCHEMBL19923690 0.77 MMP2 (0.36) MMP2ALDH1A1GFERKMT2ATSHR
SCHEMBL19923643 0.73 SMN1; SMN2 (0.37) MMP2ALDH1A1GFERKMT2ATSHR
SCHEMBL19923455 0.72 MMP2 (0.33) MMP2ALDH1A1GFERKMT2ATSHR
SCHEMBL19923698 0.70 MMP2 (0.34) MMP2ALDH1A1GFERKMT2ATSHR
SCHEMBL19923533 0.69 GRM4 (0.34) MMP2ALDH1A1GFERKMT2ATSHR
SCHEMBL19923443 0.67 LMNA (0.34) MMP2ALDH1A1GFERKMT2AMEN1
SCHEMBL19923468 0.67 LMNA (0.41) MMP2ALDH1A1GFERKMT2ATSHR
SCHEMBL19923598 0.66 SMN1; SMN2 (0.34) MMP2ALDH1A1GFERKMT2AMEN1
SCHEMBL19923726 0.65 ALDH1A1 (0.43) MMP2ALDH1A1GFERKMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 US claimed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 US claimed
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 US disclosed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS PARG, HNMT, PARN MMP2 1092/4885ALDH1A1 2648/4885GFER 1523/4885
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds HNMT, PARG, PAM MMP2 1416/4885ALDH1A1 2554/4885GFER 1433/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.