SCHEMBL19923552

SCHEMBL19923552

CC(C)[Si](C(C)C)(C(C)C)N1C(=O)N(c2ccccc2)C(=O)C1c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.40
ALDH1A1 P00352 3/20 0.37
GFER P55789 1/20 0.37
MAOA P21397 1/20 0.36
ADRA2A P08913 1/20 0.36
NISCH Q9Y2I1 1/20 0.36
MEN1 O00255 4/20 0.36
KMT2A Q03164 4/20 0.36
NPSR1 Q6W5P4 1/20 0.36
CACNA1B Q00975 1/20 0.36
APBA1 Q02410 1/20 0.36
MAPT P10636 2/20 0.35
RAB9A P51151 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.34
HDAC1 Q13547 1/20 0.34
HDAC6 Q9UBN7 1/20 0.34
ALOX15 P16050 1/20 0.33
TSHR P16473 1/20 0.33
KDM4E B2RXH2 1/20 0.33
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19923724 0.83 MMP2 (0.35) GAAALDH1A1GFERMEN1KMT2A
SCHEMBL19923553 0.83 MAOA (0.42) GAAALDH1A1GFERMAOAADRA2A
SCHEMBL19923511 0.79 ADRA2A (0.39) GAAALDH1A1GFERMAOAADRA2A
SCHEMBL19923647 0.79 GAA (0.38) GAAALDH1A1GFERMAOAMEN1
SCHEMBL2791034 0.73 NPSR1 (0.42) GAAALDH1A1GFERMAOAMEN1
SCHEMBL14353735 0.71 MEN1 (0.41) GAAALDH1A1GFERMAOAMEN1
SCHEMBL5075815 0.71 MEN1 (0.41) GAAALDH1A1GFERMAOAMEN1
SCHEMBL10335824 0.71 MEN1 (0.43) GAAALDH1A1MAOAMEN1KMT2A
SCHEMBL11337046 0.69 MEN1 (0.41) GAAALDH1A1MAOAMEN1KMT2A
SCHEMBL1639999 0.67 ALDH1A1 (0.47) GAAALDH1A1GFERMAOAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 US claimed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 US claimed
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 US disclosed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS PARG, HNMT, PARN GAA 2725/4885ALDH1A1 2648/4885GFER 1523/4885
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds HNMT, PARG, PAM GAA 2802/4885ALDH1A1 2554/4885GFER 1433/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.