SCHEMBL1997269

SCHEMBL1997269

COc1ccc(OS(=O)(=O)C(F)(F)F)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 7/20 0.57
CA2 P00918 7/20 0.57
CA9 Q16790 4/20 0.57
PKM P14618 2/20 0.50
CA12 O43570 2/20 0.48
CA7 P43166 1/20 0.48
CA14 Q9ULX7 1/20 0.48
CXCR2 P25025 2/20 0.47
PPARG P37231 1/20 0.47
NFE2L2 Q16236 1/20 0.47
CXCR1 P25024 1/20 0.46
HSD11B1 P28845 1/20 0.45
BACE1 P56817 1/20 0.43
MMP2 P08253 2/20 0.42
MMP1 P03956 1/20 0.42
MMP9 P14780 1/20 0.42
MMP8 P22894 1/20 0.42
MMP13 P45452 1/20 0.42
GAA P10253 1/20 0.42
CA4 P22748 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrogen Sulfide SCHEMBL5082548 0.98 CA1 (0.55) CA1CA2CA9PKMCA12
Iodide SCHEMBL1859836 0.98 CA1 (0.55) CA1CA2CA9PKMCA12
SCHEMBL10033152 0.91 CA1 (0.48) CA1CA2CA9PKMCA12
Biphenyl SCHEMBL115843 0.91 BACE1 (0.53) CA1CA2CA9PKMCXCR2
SCHEMBL20924560 0.91 PKM (0.68) CA1CA2CA9PKMCXCR2
Biphenyl SCHEMBL713552 0.89 BACE1 (0.51) CA1CA2CA9PKMCXCR2
Biphenyl SCHEMBL4512202 0.89 BACE1 (0.51) CA1CA2CA9PKMCXCR2
SCHEMBL3152157 0.89 CA1 (0.47) CA1CA2CA9PKMCA12
SCHEMBL576035 0.89 CA2 (0.50) CA1CA2CA9CXCR2CXCR1
Iodobenzene SCHEMBL2903737 0.88 NFE2L2 (0.46) CA1CA2CA9PKMCXCR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118047908-A Hydrophobic ion elastomer and preparation method thereof 福建理工大学 2024-05-17 CN claimed
CN-117352668-A Preparation method of pyrophosphate secondary battery positive electrode material with high air stability 深圳珈钠能源科技有限公司 2024-01-05 CN claimed
CN-110903316-B Phosphonate compound and preparation method and application thereof 中南大学 2021-03-02 CN claimed
CN-110903316-A Phosphonate compound and preparation method and application thereof 中南大学 2020-03-24 CN claimed
EP-3004120-A1 SPIRO-1,1'-BIINDANE-7,7-BISPHOSPHINE OXIDES AS HIGHLY ACTIVE SUPPORTING LIGANDS FOR PALLADIUM-CATALYZED ASYMMETRIC HECK REACTION Nanyang Technological University (SG) 2016-04-13 EP claimed
US-8952083-B2 Fluorocopolymer composition and its production process ASAHI GLASS COMPANY, LIMITED (JP) 2015-02-10 US claimed
WO-2014196930-A1 SPIRO-1,1'-BIINDANE-7,7-BISPHOSPHINE OXIDES AS HIGHLY ACTIVE SUPPORTING LIGANDS FOR PALLADIUM-CATALYZED ASYMMETRIC HECK REACTION NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2014-12-11 WO claimed
US-6369265-B1 HETEROCOUPLING REACTION, MIXING IN A LIQUID AN ARYL HALIDE, BONDING TO AROMATIC RINGS, GRIGNARD REACTION, METAL COMPOUND AND HETEROCYCLIC CARBENE UNIVERSITY OF NEW ORLEANS RESEARCH & TECHNOLOGY FOUNDATION 2002-04-09 US claimed
WO-2001066248-A2 C-C AND C-N COUPLING CATALYST COMPRISING TRANSITION METAL AND CARBENE UNIVERSITY OF NEW ORLEANS RESEARCH AND TECHNOLOGY FOUNDATION (US) 2001-09-13 WO claimed
WO-2025094700-A1 TRIFLUOROMETHANESULFONATING AGENT COMPOSITION AND METHOD FOR PRODUCING TRIFLUOROMETHANESULFONYLOXY COMPOUND 学校法人神戸薬科大学 2025-05-08 WO disclosed
CN-119928261-A Method and apparatus for manufacturing three-dimensional objects 西北大学 2025-05-06 CN disclosed
CN-109414874-B Method and apparatus for manufacturing three-dimensional objects 西北大学 2025-02-21 CN disclosed
US-20240376044-A1 METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE CHUGAI PHARMACEUTICAL CO LTD (JP) 2024-11-14 US disclosed
CN-118636467-A Method for forming three-dimensional object and apparatus for forming three-dimensional object 西北大学 2024-09-13 CN disclosed
EP-0712493-A4 A METHOD FOR PREPARING AND SELECTING PHARMACEUTICALLY USEFUL NON-PEPTIDE COMPOUNDS FROM A STRUCTURALLY DIVERSE UNIVERSAL LIBRARY SPHINX PHARMA CORP (US) 1997-01-15 EP disclosed
EP-0712493-A1 A METHOD FOR PREPARING AND SELECTING PHARMACEUTICALLY USEFUL NON-PEPTIDE COMPOUNDS FROM A STRUCTURALLY DIVERSE UNIVERSAL LIBRARY SPHINX PHARMACEUTICALS CORPORATION (US) 1996-05-22 EP disclosed
US-5480883-A Bis mono- and bicyclic aryl and heteroaryl compounds which inhibit EGF and/or PDGF receptor tyrosine kinase RHONE-POULENC RORER PHARMACEUTICALS INC. (US) 1996-01-02 US disclosed
US-5409930-A Inhibits abnoramal cell proliferation; dimethoxyquinoline/ dimethylquinoline/ quinolineoxide/ and quinoxaline derivatives RHONE-POULENC RORER PHARMACEUTICALS INC. (US) 1995-04-25 US disclosed
WO-1995004277-A1 A METHOD FOR PREPARING AND SELECTING PHARMACEUTICALLY USEFUL NON-PEPTIDE COMPOUNDS FROM A STRUCTURALLY DIVERSE UNIVERSAL LIBRARY SPHINX PHARMACEUTICALS CORPORATION (US) 1995-02-09 WO disclosed
WO-1992020642-A1 BIS MONO-AND BICYCLIC ARYL AND HETEROARYL COMPOUNDS WHICH INHIBIT EGF AND/OR PDGF RECEPTOR TYROSINE KINASE RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) 1992-11-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240376044-A1 METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE DDC, AADAT, TYR CA1 1106/4885CA2 821/4885CA9 953/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.