Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | MAP2K4 | P45985 | 2/20 | 0.35 |
| ▸ | MAPK6 | Q16659 | 2/20 | 0.35 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.33 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.33 |
| ▸ | PTGFR | P43088 | 1/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19976728 | 0.93 | PTGES (0.37) | GSK3BMAPK1MAP2K4MAPK6MAPKAPK5 | |
| SCHEMBL19976944 | 0.91 | MAPK1 (0.36) | GSK3BMAPK1MAP2K4MAPK6MAPKAPK5 | |
| SCHEMBL19976851 | 0.84 | POLB (0.35) | MAPK1MAP2K4MAPK6TRPA1PDE2A | |
| SCHEMBL19976798 | 0.84 | PTGES (0.36) | MAPK1LMNATP53MAPTMEN1 | |
| SCHEMBL19976928 | 0.82 | CTNNB1 (0.37) | MAPK1LMNATP53HTTKMT2A | |
| SCHEMBL19976784 | 0.80 | MAPK1 (0.38) | MAPK1MAP2K4 | |
| SCHEMBL19976777 | 0.78 | POLB (0.39) | MAPK1LMNAMEN1KMT2A | |
| SCHEMBL16752811 | 0.76 | GSK3B (0.48) | GSK3BMAPK1MAP2K4MAPK6MAPKAPK5 | |
| SCHEMBL16752808 | 0.76 | GSK3B (0.48) | GSK3BMAPK1MAP2K4MAPK6MAPKAPK5 | |
| SCHEMBL16752809 | 0.76 | GSK3B (0.48) | GSK3BMAPK1MAP2K4MAPK6MAPKAPK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9920012-B2 | Indazole guanidine F1F0-ATPase inhibitors and therapeutic uses thereof | LYCERA CORPORATION (US) | 2018-03-20 | — | — | US | disclosed |