Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 2/20 | 0.41 |
| ▸ | BIRC2 | Q13490 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.39 |
| ▸ | EIF4H | Q15056 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PYGL | P06737 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19977004 | 0.86 | SMN1; SMN2 (0.48) | XIAPBIRC2CYP1A2CYP3A4KDM4E | |
| SCHEMBL19976939 | 0.85 | ALDH1A1 (0.56) | LMNAKDM4EALDH1A1PABPC1EIF4H | |
| SCHEMBL18272418 | 0.85 | CTSV (0.45) | PYGL | |
| SCHEMBL19976919 | 0.79 | LMNA (0.47) | LMNAESR1KDM4EALDH1A1HPGD | |
| SCHEMBL19976908 | 0.78 | ALDH1A1 (0.55) | LMNACYP1A2CYP3A4KDM4EALDH1A1 | |
| SCHEMBL19976994 | 0.75 | PGR (0.57) | LMNAKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL19976930 | 0.74 | ALDH1A1 (0.55) | LMNAALDH1A1HPGDPYGLPOLB | |
| SCHEMBL19977047 | 0.74 | MRGPRX1 (0.45) | LMNAALDH1A1HPGDPOLBTHRB | |
| SCHEMBL19976933 | 0.74 | PABPC1 (0.73) | LMNAKDM4EALDH1A1PABPC1EIF4H | |
| SCHEMBL19976943 | 0.71 | KMT2A (0.48) | LMNAESR1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |