Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.38 |
| ▸ | AGER | Q15109 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19976941 | 0.88 | PGR (0.40) | RAB9AKMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL19977101 | 0.85 | SMN1; SMN2 (0.43) | RAB9AKMT2AMEN1SMN1; SMN2KDM4E | |
| SCHEMBL16994035 | 0.84 | CTSL (0.49) | POLB | |
| SCHEMBL19977017 | 0.78 | TRPV1 (0.52) | KMT2AMEN1 | |
| SCHEMBL19976908 | 0.77 | ALDH1A1 (0.55) | KMT2AMEN1HTTSMN1; SMN2HSD17B10 | |
| SCHEMBL19976906 | 0.76 | PGR (0.52) | RAB9AKMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL19977103 | 0.76 | KMT2A (0.46) | RAB9AKMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL19977044 | 0.74 | TRPV1 (0.53) | RAB9AKMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL16994031 | 0.73 | MMP2 (0.49) | POLB | |
| SCHEMBL19977090 | 0.73 | DHPS (0.46) | KMT2AMEN1HTTSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |