Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.58 |
| ▸ | MEN1 | O00255 | 8/20 | 0.58 |
| ▸ | GAA | P10253 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19976982 | 0.86 | L3MBTL1 (0.52) | KMT2AMEN1GAAMAPTL3MBTL1 | |
| SCHEMBL1520408 | 0.85 | KCNMA1 (0.72) | KMT2AMEN1GAAMAPTLMNA | |
| SCHEMBL19976901 | 0.84 | GAA (0.59) | KMT2AMEN1GAAMAPTLMNA | |
| SCHEMBL16994023 | 0.81 | KMT2A (0.50) | KMT2AMEN1GAAMAPTLMNA | |
| SCHEMBL19976953 | 0.81 | LMNA (0.56) | KMT2AMEN1GAAMAPTLMNA | |
| SCHEMBL19976968 | 0.80 | KCNMA1 (0.57) | KMT2AMEN1GAAMAPTLMNA | |
| SCHEMBL19976911 | 0.79 | LMNA (0.54) | KMT2AMEN1MAPTLMNAKCNMA1 | |
| SCHEMBL19977031 | 0.77 | KCNMA1 (0.54) | KMT2AMEN1GAAMAPTLMNA | |
| SCHEMBL5115961 | 0.74 | KMT2A (0.59) | KMT2AMEN1MAPTLMNATDP1 | |
| SCHEMBL19976931 | 0.74 | APLNR (0.72) | KMT2AMEN1GAAMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |