Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.43 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5490486 | 0.84 | TAS2R14 (0.59) | TAS2R14POLBALDH1A1MAPTALOX12 | |
| SCHEMBL19977018 | 0.84 | SMN1; SMN2 (0.50) | POLBALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL19976955 | 0.83 | POLB (0.53) | POLBALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL16999354 | 0.83 | USP30 (0.56) | — | |
| SCHEMBL19977071 | 0.81 | LMNA (0.45) | POLBALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL19977072 | 0.81 | LMNA (0.54) | POLBLMNASMN1; SMN2KCNK3KCNK9 | |
| SCHEMBL19977070 | 0.80 | KCNK3 (0.48) | POLBALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL19976970 | 0.79 | NPC1 (0.53) | ALDH1A1MAPTLMNASMN1; SMN2KCNK3 | |
| SCHEMBL19976922 | 0.79 | HPGD (0.66) | POLBMAPK1ALDH1A1MAPTLMNA | |
| SCHEMBL19977134 | 0.78 | HDAC1 (0.46) | POLBLMNASMN1; SMN2HDAC6KCNK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |