Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | DHPS | P49366 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | NPY2R | P49146 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19976913 | 0.88 | LMNA (0.43) | LMNAKMT2ADHPSALDH1A1MAPT | |
| SCHEMBL19977084 | 0.86 | DHPS (0.46) | LMNAKMT2AMEN1DHPSNPSR1 | |
| SCHEMBL16993994 | 0.84 | CTSV (0.49) | — | |
| SCHEMBL16999366 | 0.84 | CTSV (0.49) | — | |
| SCHEMBL18272367 | 0.82 | NHERF1 (0.51) | TRPV1 | |
| SCHEMBL19976968 | 0.81 | KCNMA1 (0.57) | LMNAKMT2AMEN1TRPV1NPSR1 | |
| SCHEMBL19976911 | 0.80 | LMNA (0.54) | LMNAKMT2AMEN1NPSR1ALDH1A1 | |
| SCHEMBL19977031 | 0.78 | KCNMA1 (0.54) | LMNAKMT2AMEN1NPSR1ALDH1A1 | |
| SCHEMBL19976905 | 0.77 | KMT2A (0.56) | KMT2AMEN1DHPSALDH1A1MAPT | |
| SCHEMBL19976985 | 0.76 | TRPV1 (0.52) | LMNATRPV1DHPSNPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |