Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 3/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.41 |
| ▸ | TDO2 | P48775 | 2/20 | 0.40 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.40 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
| ▸ | PRKACG | P22612 | 1/20 | 0.39 |
| ▸ | PRKACB | P22694 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983776 | 0.82 | CHRNB2 (0.42) | ROCK2ROCK1TDO2HTR2ACHRNB2 | |
| SCHEMBL19983953 | 0.78 | GPR84 (0.43) | TDO2HTR2ACHRNB2CHRNA7CHRNA4 | |
| SCHEMBL19984287 | 0.76 | MAPT (0.45) | TDO2HTR2ACHRNB2CHRNA7CHRNA4 | |
| SCHEMBL19983923 | 0.73 | GPR84 (0.51) | HTR2ACHRNB2CHRNA7CHRNA4GPR84 | |
| SCHEMBL31415127 | 0.72 | GPR84 (0.72) | TDO2FTOHTR2ACHRNB2CHRNA7 | |
| SCHEMBL3281375 | 0.70 | HTR2A (0.61) | FTOHTR2ACHRNB2CHRNA7CHRNA4 | |
| SCHEMBL19983810 | 0.70 | ALKBH5 (0.39) | FTOCHRNB2CHRNA7CHRNA4GPR84 | |
| SCHEMBL19983869 | 0.70 | MMP2 (0.46) | ROCK2ROCK1PRKACAPRKACGPRKACB | |
| SCHEMBL15897700 | 0.69 | CHRNB2 (0.72) | HTR2ACHRNB2CHRNA7CHRNA4GPR84 | |
| SCHEMBL19983831 | 0.69 | HTR2A (0.49) | HTR2AGPR84MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |