Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH5 | Q6P6C2 | 2/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.38 |
| ▸ | ATR | Q13535 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | PI4KA | P42356 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983776 | 0.74 | CHRNB2 (0.42) | CHRNB2CHRNA7CHRNA4GPR84 | |
| SCHEMBL19984287 | 0.73 | MAPT (0.45) | CHRNB2CHRNA7CHRNA4CYP3A4CYP2C9 | |
| SCHEMBL3281375 | 0.70 | HTR2A (0.61) | ALKBH5FTOCHRNB2CHRNA7CHRNA4 | |
| SCHEMBL19983923 | 0.70 | GPR84 (0.51) | CHRNB2CHRNA7CHRNA4GPR84 | |
| SCHEMBL19984200 | 0.70 | ROCK2 (0.41) | FTOCHRNB2CHRNA7CHRNA4SMN1; SMN2 | |
| SCHEMBL31415127 | 0.69 | GPR84 (0.72) | ALKBH5FTOCHRNB2CHRNA7CHRNA4 | |
| SCHEMBL15897700 | 0.69 | CHRNB2 (0.72) | CHRNB2CHRNA7CHRNA4GPR84 | |
| SCHEMBL19983953 | 0.68 | GPR84 (0.43) | CHRNB2CHRNA7CHRNA4GPR84 | |
| SCHEMBL19984170 | 0.68 | HTR2A (0.44) | ALKBH5FTOCHRNB2CHRNA7CHRNA4 | |
| SCHEMBL19984283 | 0.68 | HTR2A (0.47) | ALKBH5FTOCHRNB2CHRNA7CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |