Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 2/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | GAK | O14976 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.32 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.32 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984203 | 0.87 | ABL1 (0.35) | KDRP2RX7MAPT | |
| SCHEMBL19984022 | 0.86 | AKR1C3 (0.38) | KDRAKR1C3AKR1C2GAKGAA | |
| SCHEMBL19983777 | 0.84 | ADRB2 (0.37) | P2RX7GAKADRB2 | |
| SCHEMBL19983885 | 0.83 | FBP1 (0.39) | KDRP2RX7GAKADRB2HTR2A | |
| SCHEMBL16626746 | 0.82 | RORC (0.41) | CNR2CNR1GAAMAPT | |
| Hydrochloric Acid SCHEMBL16618727 | 0.81 | RORC (0.41) | CNR2CNR1GAAMAPT | |
| SCHEMBL19984021 | 0.81 | GAK (0.40) | KDRAKR1C3AKR1C2GAKHTR2A | |
| SCHEMBL19983946 | 0.81 | SLC6A4 (0.38) | HTR2ASLC6A4KCNH2 | |
| SCHEMBL19984182 | 0.80 | P2RX7 (0.31) | P2RX7 | |
| SCHEMBL19984029 | 0.80 | APP (0.35) | AKR1C3AKR1C2MAPTTEAD4TEAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |