Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 3/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.33 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | BRAF | P15056 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | GALR2 | O43603 | 2/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | BCR | P11274 | 1/20 | 0.32 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983777 | 0.91 | ADRB2 (0.37) | FBP1ADRB2P2RX7MAPK14GALR2 | |
| SCHEMBL19983775 | 0.91 | EGFR (0.34) | FBP1EGFRERBB2ERBB3ERBB4 | |
| SCHEMBL19984021 | 0.90 | GAK (0.40) | SLC6A4EGFRERBB2ERBB3ERBB4 | |
| SCHEMBL19984027 | 0.85 | MAPK14 (0.37) | FBP1MAPK14GAK | |
| SCHEMBL19984271 | 0.85 | HTR2A (0.34) | FBP1SLC6A4EGFRERBB3HTR2A | |
| SCHEMBL19984182 | 0.84 | P2RX7 (0.31) | P2RX7 | |
| SCHEMBL19983907 | 0.84 | FPR1 (0.36) | FBP1SLC6A4SLC6A2EGFRHTR2A | |
| SCHEMBL19984154 | 0.83 | P2RX7 (0.34) | P2RX7 | |
| SCHEMBL19983791 | 0.83 | KDR (0.33) | SLC6A4EGFRADRB2P2RX7HTR2A | |
| SCHEMBL19983946 | 0.83 | SLC6A4 (0.38) | FBP1SLC6A4SLC6A2SLC6A3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |