Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAK | O14976 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983889 | 0.91 | HTR2A (0.33) | HTR2ASLC6A4KCNH2ALDH1A1SMN1; SMN2 | |
| SCHEMBL19983907 | 0.89 | FPR1 (0.36) | HTR2ASLC6A4KCNH2LMNAALDH1A1 | |
| SCHEMBL19984021 | 0.87 | GAK (0.40) | HTR2ASLC6A4KCNH2ALDH1A1KDM4E | |
| SCHEMBL19983885 | 0.85 | FBP1 (0.39) | HTR2ASLC6A4KCNH2GAKMAPK14 | |
| SCHEMBL19984027 | 0.84 | MAPK14 (0.37) | GAKMAPK14MEN1KMT2AMAPT | |
| SCHEMBL19983981 | 0.83 | CNR2 (0.34) | ALDH1A1KDM4EGAKMAPK14MEN1 | |
| SCHEMBL19983777 | 0.82 | ADRB2 (0.37) | GAKMAPK14RAB9AFBP1 | |
| SCHEMBL19983901 | 0.82 | TSHR (0.35) | MEN1KMT2ASMN1; SMN2MAPTPOLB | |
| SCHEMBL19984025 | 0.82 | MAPK14 (0.32) | MAPK14MAPTGAA | |
| SCHEMBL19984022 | 0.81 | AKR1C3 (0.38) | ALDH1A1GAKMAPK14MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |