Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.36 |
| ▸ | BCL6 | P41182 | 4/20 | 0.36 |
| ▸ | BCOR | Q6W2J9 | 4/20 | 0.36 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | FADS1 | O60427 | 1/20 | 0.34 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983715 | 0.83 | HTR2A (0.42) | MAPK8MAPK10MAPK14BCL6BCOR | |
| SCHEMBL19984228 | 0.80 | NR4A2 (0.46) | POLBMAPK8MAPK10MAPK14BCL6 | |
| SCHEMBL14864247 | 0.73 | GAA (0.48) | POLBHTTEGFRAPP | |
| SCHEMBL28375689 | 0.72 | GPR84 (0.58) | NR4A2HTR2AIDO1TDO2 | |
| SCHEMBL19983739 | 0.72 | CHRNB2 (0.50) | HTR2AEGFRIDO1 | |
| SCHEMBL18590733 | 0.71 | HPGD (0.48) | POLBHTTEGFRAPP | |
| SCHEMBL5768693 | 0.71 | RAB9A (0.47) | POLBHTT | |
| SCHEMBL19984030 | 0.69 | GPR84 (0.48) | MAPK14HTR2A | |
| SCHEMBL19984005 | 0.69 | HTR2A (0.44) | HTR2A | |
| SCHEMBL19984037 | 0.68 | SLC6A2 (0.34) | POLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |