Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 5/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983970 | 0.90 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3GRM4 | |
| SCHEMBL19983836 | 0.89 | SLC6A2 (0.39) | SLC6A2SLC6A4SLC6A3KDM4EGAA | |
| SCHEMBL19983841 | 0.84 | SLC6A4 (0.43) | SLC6A2SLC6A4SLC6A3ALDH1A1GRM4 | |
| SCHEMBL19983715 | 0.81 | HTR2A (0.42) | KDM4EALDH1A1HSD17B10PTGS2PTGS1 | |
| SCHEMBL19984030 | 0.70 | GPR84 (0.48) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL19983739 | 0.70 | CHRNB2 (0.50) | SLC6A4ALDH1A1GAAPTGS2 | |
| SCHEMBL19984306 | 0.69 | LCK (0.35) | SLC6A2SLC6A4SLC6A3DHODHKDM4E | |
| SCHEMBL19984005 | 0.68 | HTR2A (0.44) | KDM4EALDH1A1HSD17B10ATMSMN1; SMN2 | |
| SCHEMBL19984249 | 0.68 | TDO2 (0.41) | SLC6A2SLC6A3KDM4ESSTR3 | |
| SCHEMBL19983988 | 0.68 | POLB (0.38) | HTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |